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3-fluoro- and 3,3-difluoro-3,4-dideoxy-KRN7000 analogues as new potent immunostimulator agents: total synthesis and biological evaluation in human invariant natural killer T cells and mice.
Hunault J, Diswall M, Frison JC, Blot V, Rocher J, Marionneau-Lambot S, Oullier T, Douillard JY, Guillarme S, Saluzzo C, Dujardin G, Jacquemin D, Graton J, Le Questel JY, Evain M, Lebreton J, Dubreuil D, Le Pendu J, Pipelier M. Hunault J, et al. Among authors: dubreuil d. J Med Chem. 2012 Feb 9;55(3):1227-41. doi: 10.1021/jm201368m. Epub 2012 Feb 1. J Med Chem. 2012. PMID: 22243602
3,4-Dideoxy-3,3,4,4-tetrafluoro- and 4-OH epimeric 3-deoxy-3,3-difluoro-α-GalCer analogues: Synthesis and biological evaluation on human iNKT cells stimulation.
Golten S, Patinec A, Akoumany K, Rocher J, Graton J, Jacquemin D, Le Questel JY, Tessier A, Lebreton J, Blot V, Pipelier M, Douillard JY, Le Pendu J, Linclau B, Dubreuil D. Golten S, et al. Among authors: dubreuil d. Eur J Med Chem. 2019 Sep 15;178:195-213. doi: 10.1016/j.ejmech.2019.05.069. Epub 2019 May 29. Eur J Med Chem. 2019. PMID: 31185411
Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity.
Kouba S, Braire J, Félix R, Chantôme A, Jaffrès PA, Lebreton J, Dubreuil D, Pipelier M, Zhang X, Trebak M, Vandier C, Mathé-Allainmat M, Potier-Cartereau M. Kouba S, et al. Among authors: dubreuil d. Eur J Med Chem. 2020 Jan 15;186:111854. doi: 10.1016/j.ejmech.2019.111854. Epub 2019 Nov 9. Eur J Med Chem. 2020. PMID: 31753515
Synthesis and biological evaluation of 3-amino-, 3-alkoxy- and 3-aryloxy-6-(hetero)arylpyridazines as potent antitumor agents.
Sengmany S, Sitter M, Léonel E, Le Gall E, Loirand G, Martens T, Dubreuil D, Dilasser F, Rousselle M, Sauzeau V, Lebreton J, Pipelier M, Le Guével R. Sengmany S, et al. Among authors: dubreuil d. Bioorg Med Chem Lett. 2019 Mar 1;29(5):755-760. doi: 10.1016/j.bmcl.2018.12.050. Epub 2018 Dec 23. Bioorg Med Chem Lett. 2019. PMID: 30655216 Free article.
Synthesis and Biological Evaluation of 4'-C,3'-O-Propylene-Linked Bicyclic Nucleosides.
Hatton W, Hunault J, Egorov M, Len C, Pipelier M, Blot V, Silvestre V, Fargeas V, Ané A, McBrayer T, Detorio M, Cho JH, Bourgougnon N, Dubreuil D, Schinazi RF, Lebreton J. Hatton W, et al. Among authors: dubreuil d. European J Org Chem. 2011 Dec;2011(36):7390-7399. doi: 10.1002/ejoc.201100859. Epub 2011 Oct 28. European J Org Chem. 2011. PMID: 34566488 Free PMC article.
Asymmetric synthesis of cyclohexene nucleoside analogues.
Dalençon S, Youcef RA, Pipelier M, Maisonneuve V, Dubreuil D, Huet F, Legoupy S. Dalençon S, et al. Among authors: dubreuil d. J Org Chem. 2011 Oct 7;76(19):8059-63. doi: 10.1021/jo2012708. Epub 2011 Sep 6. J Org Chem. 2011. PMID: 21863882
Electrochemical synthesis and characterisation of alternating tripyridyl-dipyrrole molecular strands with multiple nitrogen-based donor-acceptor binding sites.
Tabatchnik-Rebillon A, Aubé C, Bakkali H, Delaunay T, Manh GT, Blot V, Thobie-Gautier C, Renault E, Soulard M, Planchat A, Le Questel JY, Le Guével R, Guguen-Guillouzo C, Kauffmann B, Ferrand Y, Huc I, Urgin K, Condon S, Léonel E, Evain M, Lebreton J, Jacquemin D, Pipelier M, Dubreuil D. Tabatchnik-Rebillon A, et al. Among authors: dubreuil d. Chemistry. 2010 Oct 18;16(39):11876-89. doi: 10.1002/chem.201000859. Chemistry. 2010. PMID: 20839373
87 results