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Discovery of Inhibitory Fragments That Selectively Target Spire2-FMN2 Interaction.
Kitel R, Surmiak E, Borggräfe J, Kalinowska-Tluscik J, Golik P, Czub M, Uzar W, Musielak B, Madej M, Popowicz GM, Dubin G, Holak TA. Kitel R, et al. Among authors: dubin g. J Med Chem. 2023 Dec 14;66(23):15715-15727. doi: 10.1021/acs.jmedchem.3c00877. Epub 2023 Dec 1. J Med Chem. 2023. PMID: 38039505 Free PMC article.
Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln.
Dubin G, Stec-Niemczyk J, Kisielewska M, Pustelny K, Popowicz GM, Bista M, Kantyka T, Boulware KT, Stennicke HR, Czarna A, Phopaisarn M, Daugherty PS, Thøgersen IB, Enghild JJ, Thornberry N, Dubin A, Potempa J. Dubin G, et al. Among authors: dubin a. J Mol Biol. 2008 May 30;379(2):343-56. doi: 10.1016/j.jmb.2008.03.059. Epub 2008 Apr 3. J Mol Biol. 2008. PMID: 18448121
210 results