Dubin G - Search Results

1

1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers.

Twarda-Clapa A, Krzanik S, Kubica K, Guzik K, Labuzek B, Neochoritis CG, Khoury K, Kowalska K, Czub M, Dubin G, Dömling A, Skalniak L, Holak TA. Twarda-Clapa A, et al. Among authors: dubin g. J Med Chem. 2017 May 25;60(10):4234-4244. doi: 10.1021/acs.jmedchem.7b00104. Epub 2017 May 16. J Med Chem. 2017. PMID: 28482147

2

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus.

Dubin G, Krajewski M, Popowicz G, Stec-Niemczyk J, Bochtler M, Potempa J, Dubin A, Holak TA. Dubin G, et al. Among authors: dubin a. Biochemistry. 2003 Nov 25;42(46):13449-56. doi: 10.1021/bi035310j. Biochemistry. 2003. PMID: 14621990

3

Functional and structural characterization of Spl proteases from Staphylococcus aureus.

Popowicz GM, Dubin G, Stec-Niemczyk J, Czarny A, Dubin A, Potempa J, Holak TA. Popowicz GM, et al. Among authors: dubin g, dubin a. J Mol Biol. 2006 Apr 21;358(1):270-9. doi: 10.1016/j.jmb.2006.01.098. Epub 2006 Feb 13. J Mol Biol. 2006. PMID: 16516230

4

High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx.

Czarna A, Popowicz GM, Pecak A, Wolf S, Dubin G, Holak TA. Czarna A, et al. Among authors: dubin g. Cell Cycle. 2009 Apr 15;8(8):1176-84. doi: 10.4161/cc.8.8.8185. Epub 2009 Apr 16. Cell Cycle. 2009. PMID: 19305137

5

Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.

Zdzalik M, Pustelny K, Kedracka-Krok S, Huben K, Pecak A, Wladyka B, Jankowski S, Dubin A, Potempa J, Dubin G. Zdzalik M, et al. Among authors: dubin g, dubin a. Cell Cycle. 2010 Nov 15;9(22):4584-91. doi: 10.4161/cc.9.22.13871. Epub 2010 Nov 15. Cell Cycle. 2010. PMID: 21088494

6

On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53.

Bista M, Smithson D, Pecak A, Salinas G, Pustelny K, Min J, Pirog A, Finch K, Zdzalik M, Waddell B, Wladyka B, Kedracka-Krok S, Dyer MA, Dubin G, Guy RK. Bista M, et al. Among authors: dubin g. PLoS One. 2012;7(6):e37518. doi: 10.1371/journal.pone.0037518. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675482 Free PMC article.

7

Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011-present).

Zak K, Pecak A, Rys B, Wladyka B, Dömling A, Weber L, Holak TA, Dubin G. Zak K, et al. Among authors: dubin g. Expert Opin Ther Pat. 2013 Apr;23(4):425-48. doi: 10.1517/13543776.2013.765405. Epub 2013 Feb 4. Expert Opin Ther Pat. 2013. PMID: 23374098 Review.

8

Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.

Zak KM, Kitel R, Przetocka S, Golik P, Guzik K, Musielak B, Dömling A, Dubin G, Holak TA. Zak KM, et al. Among authors: dubin g. Structure. 2015 Dec 1;23(12):2341-2348. doi: 10.1016/j.str.2015.09.010. Epub 2015 Oct 22. Structure. 2015. PMID: 26602187 Free PMC article.

9

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1).

Zak KM, Grudnik P, Guzik K, Zieba BJ, Musielak B, Dömling A, Dubin G, Holak TA. Zak KM, et al. Among authors: dubin g. Oncotarget. 2016 May 24;7(21):30323-35. doi: 10.18632/oncotarget.8730. Oncotarget. 2016. PMID: 27083005 Free PMC article.

10

Inhibitors of programmed cell death 1 (PD-1): a patent review (2010-2015).

Zarganes-Tzitzikas T, Konstantinidou M, Gao Y, Krzemien D, Zak K, Dubin G, Holak TA, Dömling A. Zarganes-Tzitzikas T, et al. Among authors: dubin g. Expert Opin Ther Pat. 2016 Sep;26(9):973-7. doi: 10.1080/13543776.2016.1206527. Epub 2016 Jul 6. Expert Opin Ther Pat. 2016. PMID: 27367741 Free PMC article. No abstract available.

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