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The oncogenic fusion protein DNAJB1-PRKACA can be specifically targeted by peptide-based immunotherapy in fibrolamellar hepatocellular carcinoma.
Bauer J, Köhler N, Maringer Y, Bucher P, Bilich T, Zwick M, Dicks S, Nelde A, Dubbelaar M, Scheid J, Wacker M, Heitmann JS, Schroeder S, Rieth J, Denk M, Richter M, Klein R, Bonzheim I, Luibrand J, Holzer U, Ebinger M, Brecht IB, Bitzer M, Boerries M, Feucht J, Salih HR, Rammensee HG, Hailfinger S, Walz JS. Bauer J, et al. Among authors: dubbelaar m. Nat Commun. 2022 Oct 27;13(1):6401. doi: 10.1038/s41467-022-33746-3. Nat Commun. 2022. PMID: 36302754 Free PMC article.
Aging, microglia and cytoskeletal regulation are key factors in the pathological evolution of the APP23 mouse model for Alzheimer's disease.
Janssen L, Dubbelaar ML, Holtman IR, de Boer-Bergsma J, Eggen BJ, Boddeke HW, De Deyn PP, Van Dam D. Janssen L, et al. Among authors: dubbelaar ml. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):395-405. doi: 10.1016/j.bbadis.2016.11.014. Epub 2016 Nov 10. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27838490 Free article.
The Kaleidoscope of Microglial Phenotypes.
Dubbelaar ML, Kracht L, Eggen BJL, Boddeke EWGM. Dubbelaar ML, et al. Front Immunol. 2018 Jul 31;9:1753. doi: 10.3389/fimmu.2018.01753. eCollection 2018. Front Immunol. 2018. PMID: 30108586 Free PMC article. Review.
Profiling Microglia From Alzheimer's Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue.
Alsema AM, Jiang Q, Kracht L, Gerrits E, Dubbelaar ML, Miedema A, Brouwer N, Hol EM, Middeldorp J, van Dijk R, Woodbury M, Wachter A, Xi S, Möller T, Biber KP, Kooistra SM, Boddeke EWGM, Eggen BJL. Alsema AM, et al. Among authors: dubbelaar ml. Front Mol Neurosci. 2020 Oct 28;13:134. doi: 10.3389/fnmol.2020.00134. eCollection 2020. Front Mol Neurosci. 2020. PMID: 33192286 Free PMC article.
21 results