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3,201 results

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Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
Zhong X, Jagarlapudi S, Weng Y, Ly M, Rouse JC, McClure K, Ishino T, Zhang Y, Sousa E, Cohen J, Tzvetkova B, Cote K, Scarcelli JJ, Johnson K, Palandra J, Apgar JR, Yaddanapudi S, Gonzalez-Villalobos RA, Opsahl AC, Lam K, Yao Q, Duan W, Sievers A, Zhou J, Ferguson D, D'Antona A, Zollner R, Zhu HL, Kriz R, Lin L, Clerin V. Zhong X, et al. Among authors: duan w. J Biol Chem. 2020 Mar 6;295(10):3115-3133. doi: 10.1074/jbc.RA119.012144. Epub 2020 Jan 31. J Biol Chem. 2020. PMID: 32005658 Free PMC article.
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.
Root AR, Guntas G, Katragadda M, Apgar JR, Narula J, Chang CS, Hanscom S, McKenna M, Wade J, Meade C, Ma W, Guo Y, Liu Y, Duan W, Hendershot C, King AC, Zhang Y, Sousa E, Tam A, Benard S, Yang H, Kelleher K, Jin F, Piche-Nicholas N, Keating SE, Narciandi F, Lawrence-Henderson R, Arai M, Stochaj WR, Svenson K, Mosyak L, Lam K, Francis C, Marquette K, Wroblewska L, Zhu HL, Sheehan AD, LaVallie ER, D'Antona AM, Betts A, King L, Rosfjord E, Cunningham O, Lin L, Sapra P, Tchistiakova L, Mathur D, Bloom L. Root AR, et al. Among authors: duan w. MAbs. 2021 Jan-Dec;13(1):1850395. doi: 10.1080/19420862.2020.1850395. MAbs. 2021. PMID: 33459147 Free PMC article.
Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing.
Weng Y, Ishino T, Sievers A, Talukdar S, Chabot JR, Tam A, Duan W, Kerns K, Sousa E, He T, Logan A, Lee D, Li D, Zhou Y, Bernardo B, Joyce A, Kavosi M, O'Hara DM, Clark T, Guo J, Giragossian C, Stahl M, Calle RA, Kriz R, Somers W, Lin L. Weng Y, et al. Among authors: duan w. Sci Rep. 2018 Mar 9;8(1):4241. doi: 10.1038/s41598-018-22456-w. Sci Rep. 2018. PMID: 29523796 Free PMC article.
Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule.
Tevelev B, Patel H, Shields K, Wei W, Cooley C, Zhang S, Bitzas G, Duan W, Khetemenee L, Jackobek R, D'Antona A, Sievers A, King A, Tam A, Zhang Y, Sousa E, Cohen J, Wroblewska L, Marshall J, Jackson M, Scarcelli JJ. Tevelev B, et al. Among authors: duan w. Biotechnol Prog. 2021 Jul;37(4):e3158. doi: 10.1002/btpr.3158. Epub 2021 May 12. Biotechnol Prog. 2021. PMID: 33891804 Free PMC article.
Initiating PeriCBD to probe perinatal influences on neurodevelopment during 3-10 years in China.
Wang YS, Su XT, Ke L, He QH, Chang D, Nie J, Luo X, Chen F, Xu J, Zhang C, Zhang S, Zhang S, An H, Guo R, Yue S, Duan W, Jia S, Yang S, Yu Y, Zhao Y, Zhou Y, Chen LZ, Fan XR, Gao P, Lv C, Wu Z, Zhao Y, Quan X, Zhao F, Mu Y, Yan Y, Xu W, Liu J, Xing L, Chen X, Wu X, Zhao L, Huang Z, Ren Y, Hao H, Li H, Wang J, Dong Q, Chen L, Huang R, Liu S, Wang Y, Dong Q, Zuo XN. Wang YS, et al. Among authors: duan w. Sci Data. 2024 May 7;11(1):463. doi: 10.1038/s41597-024-03211-5. Sci Data. 2024. PMID: 38714688 Free PMC article.
3,201 results