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Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity.
Erickson E, Gado JE, Avilán L, Bratti F, Brizendine RK, Cox PA, Gill R, Graham R, Kim DJ, König G, Michener WE, Poudel S, Ramirez KJ, Shakespeare TJ, Zahn M, Boyd ES, Payne CM, DuBois JL, Pickford AR, Beckham GT, McGeehan JE. Erickson E, et al. Among authors: dubois jl. Nat Commun. 2022 Dec 21;13(1):7850. doi: 10.1038/s41467-022-35237-x. Nat Commun. 2022. PMID: 36543766 Free PMC article.
A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.
Mallinson SJB, Machovina MM, Silveira RL, Garcia-Borràs M, Gallup N, Johnson CW, Allen MD, Skaf MS, Crowley MF, Neidle EL, Houk KN, Beckham GT, DuBois JL, McGeehan JE. Mallinson SJB, et al. Among authors: dubois jl. Nat Commun. 2018 Jun 27;9(1):2487. doi: 10.1038/s41467-018-04878-2. Nat Commun. 2018. PMID: 29950589 Free PMC article.
Enabling microbial syringol conversion through structure-guided protein engineering.
Machovina MM, Mallinson SJB, Knott BC, Meyers AW, Garcia-Borràs M, Bu L, Gado JE, Oliver A, Schmidt GP, Hinchen DJ, Crowley MF, Johnson CW, Neidle EL, Payne CM, Houk KN, Beckham GT, McGeehan JE, DuBois JL. Machovina MM, et al. Among authors: dubois jl. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13970-13976. doi: 10.1073/pnas.1820001116. Epub 2019 Jun 24. Proc Natl Acad Sci U S A. 2019. PMID: 31235604 Free PMC article.
Molecular mechanism of the chitinolytic peroxygenase reaction.
Bissaro B, Streit B, Isaksen I, Eijsink VGH, Beckham GT, DuBois JL, Røhr ÅK. Bissaro B, et al. Among authors: dubois jl. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1504-1513. doi: 10.1073/pnas.1904889117. Epub 2020 Jan 6. Proc Natl Acad Sci U S A. 2020. PMID: 31907317 Free PMC article.
Cytochromes P450 in the biocatalytic valorization of lignin.
Wolf ME, Hinchen DJ, DuBois JL, McGeehan JE, Eltis LD. Wolf ME, et al. Among authors: dubois jl. Curr Opin Biotechnol. 2022 Feb;73:43-50. doi: 10.1016/j.copbio.2021.06.022. Epub 2021 Jul 22. Curr Opin Biotechnol. 2022. PMID: 34303185 Review.
Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes.
Ellis ES, Hinchen DJ, Bleem A, Bu L, Mallinson SJB, Allen MD, Streit BR, Machovina MM, Doolin QV, Michener WE, Johnson CW, Knott BC, Beckham GT, McGeehan JE, DuBois JL. Ellis ES, et al. Among authors: dubois jl. JACS Au. 2021 Feb 4;1(3):252-261. doi: 10.1021/jacsau.0c00103. eCollection 2021 Mar 22. JACS Au. 2021. PMID: 34467290 Free PMC article.
143 results