Du K - Search Results

1

Hepatocyte Smoothened Activity Controls Susceptibility to Insulin Resistance and Nonalcoholic Fatty Liver Disease.

Chen T, Dalton G, Oh SH, Maeso-Diaz R, Du K, Meyers RA, Guy C, Abdelmalek MF, Henao R, Guarnieri P, Pullen SS, Gregory S, Locker J, Brown JM, Diehl AM. Chen T, et al. Among authors: du k. Cell Mol Gastroenterol Hepatol. 2023;15(4):949-970. doi: 10.1016/j.jcmgh.2022.12.008. Epub 2022 Dec 16. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36535507 Free PMC article.

2

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells.

Du K, Hyun J, Premont RT, Choi SS, Michelotti GA, Swiderska-Syn M, Dalton GD, Thelen E, Rizi BS, Jung Y, Diehl AM. Du K, et al. Gastroenterology. 2018 Apr;154(5):1465-1479.e13. doi: 10.1053/j.gastro.2017.12.022. Epub 2018 Jan 3. Gastroenterology. 2018. PMID: 29305935 Free PMC article.

3

Single-Cell RNA Sequencing Identifies Yes-Associated Protein 1-Dependent Hepatic Mesothelial Progenitors in Fibrolamellar Carcinoma.

Jewell ML, Gibson JR, Guy CD, Hyun J, Du K, Oh SH, Premont RT, Hsu DS, Ribar T, Gregory SG, Diehl AME. Jewell ML, et al. Among authors: du k. Am J Pathol. 2020 Jan;190(1):93-107. doi: 10.1016/j.ajpath.2019.09.018. Epub 2019 Oct 24. Am J Pathol. 2020. PMID: 31669305 Free PMC article.

4

Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.

Du K, Chitneni SK, Suzuki A, Wang Y, Henao R, Hyun J, Premont RT, Naggie S, Moylan CA, Bashir MR, Abdelmalek MF, Diehl AM. Du K, et al. Cell Mol Gastroenterol Hepatol. 2020;10(1):1-21. doi: 10.1016/j.jcmgh.2019.12.006. Epub 2019 Dec 25. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31881361 Free PMC article.

5

Succinate-GPR-91 receptor signalling is responsible for nonalcoholic steatohepatitis-associated fibrosis: Effects of DHA supplementation.

Liu XJ, Xie L, Du K, Liu C, Zhang NP, Gu CJ, Wang Y, Abdelmalek MF, Dong WY, Liu XP, Niu C, Yang C, Diehl AM, Wu J. Liu XJ, et al. Among authors: du k. Liver Int. 2020 Apr;40(4):830-843. doi: 10.1111/liv.14370. Epub 2020 Feb 6. Liver Int. 2020. PMID: 31903720 Free PMC article.

6

Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.

Hyun J, Sun Z, Ahmadi AR, Bangru S, Chembazhi UV, Du K, Chen T, Tsukamoto H, Rusyn I, Kalsotra A, Diehl AM. Hyun J, et al. Among authors: du k. J Clin Invest. 2020 Apr 1;130(4):2129-2145. doi: 10.1172/JCI132691. J Clin Invest. 2020. PMID: 31945016 Free PMC article.

7

Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury.

Du K, Oh SH, Dutta RK, Sun T, Yang WH, Chi JT, Diehl AM. Du K, et al. Liver Int. 2021 Sep;41(9):2214-2227. doi: 10.1111/liv.14945. Epub 2021 Jul 4. Liver Int. 2021. PMID: 33991158 Free PMC article.

8

Aging reduces liver resiliency by dysregulating Hedgehog signaling.

Maeso-Díaz R, Dalton GD, Oh S, Du K, Tang L, Chen T, Dutta RK, Hartman JH, Meyer JN, Diehl AM. Maeso-Díaz R, et al. Among authors: du k. Aging Cell. 2022 Feb;21(2):e13530. doi: 10.1111/acel.13530. Epub 2022 Jan 4. Aging Cell. 2022. PMID: 34984806 Free PMC article.

9

Targeting YAP-mediated HSC death susceptibility and senescence for treatment of liver fibrosis.

Du K, Maeso-Díaz R, Oh SH, Wang E, Chen T, Pan C, Xiang K, Dutta RK, Wang XF, Chi JT, Diehl AM. Du K, et al. Hepatology. 2023 Jun 1;77(6):1998-2015. doi: 10.1097/HEP.0000000000000326. Epub 2023 Feb 24. Hepatology. 2023. PMID: 36815382 Free PMC article.

10

Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression.

Maeso-Díaz R, Du K, Pan C, Guy CD, Oh SH, Chen T, Wang L, Ko DC, Tang L, Dutta RK, Jun JH, Suzuki A, Abdelmalek MF, Wang XF, Diehl AM. Maeso-Díaz R, et al. Among authors: du k. Hepatology. 2023 Oct 1;78(4):1209-1222. doi: 10.1097/HEP.0000000000000401. Epub 2023 Apr 11. Hepatology. 2023. PMID: 37036206

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