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Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth Fasciola hepatica.
Vaccines (Basel). 2022 Jan 20;10(2):155. doi: 10.3390/vaccines10020155.
Vaccines (Basel). 2022.
PMID: 35214614
Free PMC article.
The cathepsin-like cysteine peptidases of trematodes of the genus Fasciola.
Cwiklinski K, Donnelly S, Drysdale O, Jewhurst H, Smith D, De Marco Verissimo C, Pritsch IC, O'Neill S, Dalton JP, Robinson MW.
Cwiklinski K, et al. Among authors: drysdale o.
Adv Parasitol. 2019;104:113-164. doi: 10.1016/bs.apar.2019.01.001. Epub 2019 Feb 26.
Adv Parasitol. 2019.
PMID: 31030768
Review.
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Regulation of the Fasciola hepatica newly excysted juvenile cathepsin L3 (FhCL3) by its propeptide: a proposed 'clamp-like' mechanism of binding and inhibition.
Pritsch IC, Tikhonova IG, Jewhurst HL, Drysdale O, Cwiklinski K, Molento MB, Dalton JP, Verissimo CM.
Pritsch IC, et al. Among authors: drysdale o.
BMC Mol Cell Biol. 2020 Dec 7;21(1):90. doi: 10.1186/s12860-020-00335-5.
BMC Mol Cell Biol. 2020.
PMID: 33287692
Free PMC article.
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Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES.
Smith D, Tikhonova IG, Jewhurst HL, Drysdale OC, Dvořák J, Robinson MW, Cwiklinski K, Dalton JP.
Smith D, et al. Among authors: drysdale oc.
J Biol Chem. 2016 Sep 9;291(37):19220-34. doi: 10.1074/jbc.M116.724344. Epub 2016 Jul 15.
J Biol Chem. 2016.
PMID: 27422822
Free PMC article.
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FhCaBP3: a Fasciola hepatica calcium binding protein with EF-hand and dynein light chain domains.
Banford S, Drysdale O, Hoey EM, Trudgett A, Timson DJ.
Banford S, et al. Among authors: drysdale o.
Biochimie. 2013 Apr;95(4):751-8. doi: 10.1016/j.biochi.2012.10.027. Epub 2012 Nov 8.
Biochimie. 2013.
PMID: 23142130
Free article.
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