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The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer.
Kazantseva M, Mehta S, Eiholzer RA, Gimenez G, Bowie S, Campbell H, Reily-Bell AL, Roth I, Ray S, Drummond CJ, Reid G, Joruiz SM, Wiles A, Morrin HR, Reader KL, Hung NA, Baird MA, Slatter TL, Braithwaite AW. Kazantseva M, et al. Among authors: drummond cj. Cell Death Dis. 2019 Aug 20;10(9):631. doi: 10.1038/s41419-019-1861-1. Cell Death Dis. 2019. PMID: 31431617 Free PMC article.
Adaptive homeostasis and the p53 isoform network.
Mehta S, Campbell H, Drummond CJ, Li K, Murray K, Slatter T, Bourdon JC, Braithwaite AW. Mehta S, et al. Among authors: drummond cj. EMBO Rep. 2021 Dec 6;22(12):e53085. doi: 10.15252/embr.202153085. Epub 2021 Nov 15. EMBO Rep. 2021. PMID: 34779563 Free PMC article. Review.
Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk.
Eiholzer RA, Mehta S, Kazantseva M, Drummond CJ, McKinney C, Young K, Slater D, Morten BC, Avery-Kiejda KA, Lasham A, Fleming N, Morrin HR, Reader K, Royds JA, Landmann M, Petrich S, Reddel R, Huschtscha L, Taha A, Hung NA, Slatter TL, Braithwaite AW. Eiholzer RA, et al. Among authors: drummond cj. Cancers (Basel). 2020 Sep 1;12(9):2472. doi: 10.3390/cancers12092472. Cancers (Basel). 2020. PMID: 32882831 Free PMC article.
Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib.
Ladds MJGW, Pastor-Fernández A, Popova G, van Leeuwen IMM, Eng KE, Drummond CJ, Johansson L, Svensson R, Westwood NJ, McCarthy AR, Tholander F, Popa M, Lane DP, McCormack E, McInerney GM, Bhatia R, Laín S. Ladds MJGW, et al. Among authors: drummond cj. PLoS One. 2018 Apr 23;13(4):e0195956. doi: 10.1371/journal.pone.0195956. eCollection 2018. PLoS One. 2018. PMID: 29684045 Free PMC article.
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S. Ladds MJGW, et al. Among authors: drummond cj. Nat Commun. 2018 May 22;9(1):2071. doi: 10.1038/s41467-018-04198-5. Nat Commun. 2018. PMID: 29789663 Free PMC article.
180 results