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Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.
Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, Feliu I, Kovalski J, Lopez I, Rodriguez-Remirez M, Palomino-Echeverria S, Lonfgren SM, Ferrero M, Calabuig S, Ludwig IA, Lara-Astiaso D, Jantus-Lewintre E, Guruceaga E, Narayanan S, Ponz-Sarvise M, Pineda-Lucena A, Lecanda F, Ruggero D, Khatri P, Santamaria E, Fernandez-Irigoyen J, Ferrer I, Paz-Ares L, Drosten M, Barbacid M, Gil-Bazo I, Vicent S. Macaya I, et al. Among authors: drosten m. Nat Commun. 2023 Oct 10;14(1):6332. doi: 10.1038/s41467-023-41828-z. Nat Commun. 2023. PMID: 37816716 Free PMC article.
Targeting the MAPK Pathway in KRAS-Driven Tumors.
Drosten M, Barbacid M. Drosten M, et al. Cancer Cell. 2020 Apr 13;37(4):543-550. doi: 10.1016/j.ccell.2020.03.013. Cancer Cell. 2020. PMID: 32289276 Free article. Review.
KRAS inhibitors: going noncovalent.
Drosten M, Barbacid M. Drosten M, et al. Mol Oncol. 2022 Dec;16(22):3911-3915. doi: 10.1002/1878-0261.13341. Epub 2022 Nov 27. Mol Oncol. 2022. PMID: 36383067 Free PMC article.
Ras and p53: An unsuspected liaison.
Drosten M, Barbacid M. Drosten M, et al. Mol Cell Oncol. 2015 Jan 23;3(2):e996001. doi: 10.1080/23723556.2014.996001. eCollection 2016 Mar. Mol Cell Oncol. 2015. PMID: 27308624 Free PMC article.
Ras in epidermal proliferation.
Drosten M, Lechuga CG, Barbacid M. Drosten M, et al. Oncotarget. 2014 Jul 30;5(14):5194-5. doi: 10.18632/oncotarget.2275. Oncotarget. 2014. PMID: 25114036 Free PMC article. No abstract available.
43 results