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Page 1
Endothelial cell CD36 optimizes tissue fatty acid uptake.
Son NH, Basu D, Samovski D, Pietka TA, Peche VS, Willecke F, Fang X, Yu SQ, Scerbo D, Chang HR, Sun F, Bagdasarov S, Drosatos K, Yeh ST, Mullick AE, Shoghi KI, Gumaste N, Kim K, Huggins LA, Lhakhang T, Abumrad NA, Goldberg IJ. Son NH, et al. Among authors: drosatos k. J Clin Invest. 2018 Oct 1;128(10):4329-4342. doi: 10.1172/JCI99315. Epub 2018 Jul 26. J Clin Invest. 2018. PMID: 30047927 Free PMC article.
Lipid Use and Misuse by the Heart.
Schulze PC, Drosatos K, Goldberg IJ. Schulze PC, et al. Among authors: drosatos k. Circ Res. 2016 May 27;118(11):1736-51. doi: 10.1161/CIRCRESAHA.116.306842. Circ Res. 2016. PMID: 27230639 Free PMC article. Review.
Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice.
Willecke F, Scerbo D, Nagareddy P, Obunike JC, Barrett TJ, Abdillahi ML, Trent CM, Huggins LA, Fisher EA, Drosatos K, Goldberg IJ. Willecke F, et al. Among authors: drosatos k. Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):102-10. doi: 10.1161/ATVBAHA.114.304615. Epub 2014 Nov 13. Arterioscler Thromb Vasc Biol. 2015. PMID: 25395613 Free PMC article.
Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function.
Drosatos K, Pollak NM, Pol CJ, Ntziachristos P, Willecke F, Valenti MC, Trent CM, Hu Y, Guo S, Aifantis I, Goldberg IJ. Drosatos K, et al. Circ Res. 2016 Jan 22;118(2):241-53. doi: 10.1161/CIRCRESAHA.115.306383. Epub 2015 Nov 16. Circ Res. 2016. PMID: 26574507 Free PMC article.
Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21.
Pol CJ, Pollak NM, Jurczak MJ, Zacharia E, Karagiannides I, Kyriazis ID, Ntziachristos P, Scerbo DA, Brown BR, Aifantis I, Shulman GI, Goldberg IJ, Drosatos K. Pol CJ, et al. Among authors: drosatos k. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2125-2137. doi: 10.1016/j.bbadis.2019.04.010. Epub 2019 Apr 26. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31029826 Free PMC article.
Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction.
Kalliora C, Kyriazis ID, Oka SI, Lieu MJ, Yue Y, Area-Gomez E, Pol CJ, Tian Y, Mizushima W, Chin A, Scerbo D, Schulze PC, Civelek M, Sadoshima J, Madesh M, Goldberg IJ, Drosatos K. Kalliora C, et al. Among authors: drosatos k. JCI Insight. 2019 Aug 8;5(17):e129556. doi: 10.1172/jci.insight.129556. JCI Insight. 2019. PMID: 31393858 Free PMC article.
Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.
Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Drosatos K, et al. Among authors: drosatos tampakaki z. J Biol Chem. 2011 Oct 21;286(42):36331-9. doi: 10.1074/jbc.M111.272146. Epub 2011 Aug 26. J Biol Chem. 2011. PMID: 21873422 Free PMC article.
Krüppel-like factors: Crippling and un-crippling metabolic pathways.
Pollak NM, Hoffman M, Goldberg IJ, Drosatos K. Pollak NM, et al. Among authors: drosatos k. JACC Basic Transl Sci. 2018 Feb;3(1):132-156. doi: 10.1016/j.jacbts.2017.09.001. Epub 2018 Mar 1. JACC Basic Transl Sci. 2018. PMID: 29876529 Free PMC article.
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Chokshi A, et al. Among authors: drosatos k. Circulation. 2012 Jun 12;125(23):2844-53. doi: 10.1161/CIRCULATIONAHA.111.060889. Epub 2012 May 14. Circulation. 2012. PMID: 22586279 Free PMC article.
63 results