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144 results

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Page 1
A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner.
Ragu S, Droin N, Matos-Rodrigues G, Barascu A, Caillat S, Zarkovic G, Siberchicot C, Dardillac E, Gelot C, Guirouilh-Barbat J, Radicella JP, Ishchenko AA, Ravanat JL, Solary E, Lopez BS. Ragu S, et al. Among authors: droin n. Cell Death Differ. 2023 May;30(5):1349-1365. doi: 10.1038/s41418-023-01141-0. Epub 2023 Mar 3. Cell Death Differ. 2023. PMID: 36869180 Free PMC article.
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer.
Ma HL, Bizet M, Soares Da Costa C, Murisier F, de Bony EJ, Wang MK, Yoshimi A, Lin KT, Riching KM, Wang X, Beckman JI, Arya S, Droin N, Calonne E, Hassabi B, Zhang QY, Li A, Putmans P, Malbec L, Hubert C, Lan J, Mies F, Yang Y, Solary E, Daniels DL, Gupta YK, Deplus R, Abdel-Wahab O, Yang YG, Fuks F. Ma HL, et al. Among authors: droin n. Mol Cell. 2023 Dec 7;83(23):4239-4254.e10. doi: 10.1016/j.molcel.2023.11.003. Mol Cell. 2023. PMID: 38065062
When monoclonal gammopathy-associated chronic neutrophilic leukemia is a reactive process distinct from a clonal myeloproliferative neoplasm: Lessons from mistakes.
Willekens C, Chahine C, Dragani M, Khalife-Hachem S, Bigenwald C, Rossignol J, Castilla-Llorente C, Danu A, Michot JM, Saada V, Cotteret S, Marzac C, Renneville A, Plo I, Broutin S, Bosselut N, Cassinat B, Lazarovici J, Droin N, De Botton S. Willekens C, et al. Among authors: droin n. EJHaem. 2023 May 19;4(3):823-826. doi: 10.1002/jha2.713. eCollection 2023 Aug. EJHaem. 2023. PMID: 37601857 Free PMC article. No abstract available.
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis.
Basso-Valentina F, Donada A, Manchev VT, Lisetto M, Balayn N, Martin JE, Muller D, Oyarzun CPM, Duparc H, Arkoun B, Cumin A, Faivre L, Droin N, Biunno I, Pecci A, Balduini A, Debili N, Antony-Debré I, Marty C, Vainchenker W, Plo I, Favier R, Raslova H. Basso-Valentina F, et al. Among authors: droin n. Haematologica. 2023 Aug 1;108(8):2130-2145. doi: 10.3324/haematol.2022.282049. Haematologica. 2023. PMID: 36794499 Free PMC article.
Prognostic impact of genetic abnormalities in 536 first-line chronic lymphocytic leukaemia patients without 17p deletion treated with chemoimmunotherapy in two prospective trials: Focus on IGHV-mutated subgroups (a FILO study).
Nguyen-Khac F, Baron M, Guièze R, Feugier P, Fayault A, Raynaud S, Troussard X, Droin N, Damm F, Smagghe L, Susin S, Leblond V, Dartigeas C, Van den Neste E, Leprêtre S, Bernard OA, Roos-Weil D; on behalf the FILO (French Innovative Leukaemia Organization) Group. Nguyen-Khac F, et al. Among authors: droin n. Br J Haematol. 2024 Apr 23. doi: 10.1111/bjh.19459. Online ahead of print. Br J Haematol. 2024. PMID: 38654616
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation.
Rombaut D, Lefèvre C, Rached T, Bondu S, Letessier A, Mangione RM, Farhat B, Lesieur-Pasquier A, Castillo-Guzman D, Boussaid I, Friedrich C, Tourville A, De Carvalho M, Levavasseur F, Leduc M, Le Gall M, Battault S, Temple M, Houy A, Bouscary D, Willems L, Park S, Raynaud S, Cluzeau T, Clappier E, Fenaux P, Adès L, Margueron R, Wassef M, Alsafadi S, Chapuis N, Kosmider O, Solary E, Constantinou A, Stern MH, Droin N, Palancade B, Miotto B, Chédin F, Fontenay M. Rombaut D, et al. Among authors: droin n. Nat Commun. 2024 Apr 8;15(1):3016. doi: 10.1038/s41467-024-46547-7. Nat Commun. 2024. PMID: 38589367 Free PMC article.
TCTP regulates genotoxic stress and tumorigenicity via intercellular vesicular signaling.
Amson R, Senff-Ribeiro A, Karafin T, Lespagnol A, Honoré J, Baylot V, Banroques J, Tanner NK, Chamond N, Dimitrov JD, Hoebeke J, Droin NM, Job B, Piard J, Bommer UA, Choi KW, Abdelfatah S, Efferth T, Telerman SB, Geyer FC, Reis-Filho J, Telerman A. Amson R, et al. Among authors: droin nm. EMBO Rep. 2024 Apr;25(4):1962-1986. doi: 10.1038/s44319-024-00108-7. Epub 2024 Mar 28. EMBO Rep. 2024. PMID: 38548973 Free PMC article.
Trastuzumab deruxtecan in metastatic breast cancer with variable HER2 expression: the phase 2 DAISY trial.
Mosele F, Deluche E, Lusque A, Le Bescond L, Filleron T, Pradat Y, Ducoulombier A, Pistilli B, Bachelot T, Viret F, Levy C, Signolle N, Alfaro A, Tran DTN, Garberis IJ, Talbot H, Christodoulidis S, Vakalopoulou M, Droin N, Stourm A, Kobayashi M, Kakegawa T, Lacroix L, Saulnier P, Job B, Deloger M, Jimenez M, Mahier C, Baris V, Laplante P, Kannouche P, Marty V, Lacroix-Triki M, Diéras V, André F. Mosele F, et al. Among authors: droin n. Nat Med. 2023 Aug;29(8):2110-2120. doi: 10.1038/s41591-023-02478-2. Epub 2023 Jul 24. Nat Med. 2023. PMID: 37488289 Free PMC article. Clinical Trial.
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice.
Willekens C, Laplane L, Dagher T, Benlabiod C, Papadopoulos N, Lacout C, Rameau P, Catelain C, Alfaro A, Edmond V, Signolle N, Marchand V, Droin N, Hoogenboezem R, Schneider RK, Penson A, Abdel-Wahab O, Giraudier S, Pasquier F, Marty C, Plo I, Villeval JL, Constantinescu SN, Porteu F, Vainchenker W, Solary E. Willekens C, et al. Among authors: droin n. Leukemia. 2023 Jun;37(6):1287-1297. doi: 10.1038/s41375-023-01878-0. Epub 2023 Apr 26. Leukemia. 2023. PMID: 37100881
144 results