Driscoll JP - Search Results

1

Biotransformation and bioactivation reactions - 2018 literature highlights.

Khojasteh SC, Bumpus NN, Driscoll JP, Miller GP, Mitra K, Rietjens IMCM, Zhang D. Khojasteh SC, et al. Among authors: driscoll jp. Drug Metab Rev. 2019 May;51(2):121-161. doi: 10.1080/03602532.2019.1615937. Epub 2019 Aug 6. Drug Metab Rev. 2019. PMID: 31170851 Review.

2

Going Beyond Common Drug Metabolizing Enzymes: Case Studies of Biotransformation Involving Aldehyde Oxidase, γ-Glutamyl Transpeptidase, Cathepsin B, Flavin-Containing Monooxygenase, and ADP-Ribosyltransferase.

Fan PW, Zhang D, Halladay JS, Driscoll JP, Khojasteh SC. Fan PW, et al. Among authors: driscoll jp. Drug Metab Dispos. 2016 Aug;44(8):1253-61. doi: 10.1124/dmd.116.070169. Epub 2016 Apr 26. Drug Metab Dispos. 2016. PMID: 27117704 Review.

3

Novel advances in biotransformation and bioactivation research-2019 year in review.

Khojasteh SC, Driscoll JP, Jackson KD, Miller GP, Mitra K, Rietjens IMCM, Zhang D. Khojasteh SC, et al. Among authors: driscoll jp. Drug Metab Rev. 2020 Aug;52(3):333-365. doi: 10.1080/03602532.2020.1772281. Epub 2020 Jul 9. Drug Metab Rev. 2020. PMID: 32645275 Free PMC article. Review.

4

Novel advances in biotransformation and bioactivation research - 2020 year in review.

Khojasteh SC, Argikar UA, Driscoll JP, Heck CJS, King L, Jackson KD, Jian W, Kalgutkar AS, Miller GP, Kramlinger V, Rietjens IMCM, Teitelbaum AM, Wang K, Wei C. Khojasteh SC, et al. Among authors: driscoll jp. Drug Metab Rev. 2021 Aug;53(3):384-433. doi: 10.1080/03602532.2021.1916028. Epub 2021 Jun 24. Drug Metab Rev. 2021. PMID: 33910427 Free PMC article.

5

Bioactivation and reactivity research advances - 2021 year in review.

Jackson KD, Argikar UA, Cho S, Crouch RD, Driscoll JP, Heck CJS, King L, Maw HH, Miller GP, Seneviratne HK, Wang S, Wei C, Zhang D, Khojasteh SC. Jackson KD, et al. Among authors: driscoll jp. Drug Metab Rev. 2022 Aug;54(3):246-281. doi: 10.1080/03602532.2022.2097254. Epub 2022 Aug 5. Drug Metab Rev. 2022. PMID: 35876116 Free PMC article. Review.

6

Biotransformation and bioactivation reactions of alicyclic amines in drug molecules.

Bolleddula J, DeMent K, Driscoll JP, Worboys P, Brassil PJ, Bourdet DL. Bolleddula J, et al. Among authors: driscoll jp. Drug Metab Rev. 2014 Aug;46(3):379-419. doi: 10.3109/03602532.2014.924962. Epub 2014 Jun 9. Drug Metab Rev. 2014. PMID: 24909234 Review.

7

Novel mechanism for dehalogenation and glutathione conjugation of dihalogenated anilines in human liver microsomes: evidence for ipso glutathione addition.

Zhang C, Kenny JR, Le H, Deese A, Ford KA, Lightning LK, Fan PW, Driscoll JP, Halladay JS, Hop CE, Khojasteh SC. Zhang C, et al. Among authors: driscoll jp. Chem Res Toxicol. 2011 Oct 17;24(10):1668-77. doi: 10.1021/tx2002228. Epub 2011 Sep 25. Chem Res Toxicol. 2011. PMID: 21905702

8

Inhibitory Effects of Trapping Agents of Sulfur Drug Reactive Intermediates against Major Human Cytochrome P450 Isoforms.

Sodhi JK, Delarosa EM, Halladay JS, Driscoll JP, Mulder T, Dansette PM, Khojasteh SC. Sodhi JK, et al. Among authors: driscoll jp. Int J Mol Sci. 2017 Jul 20;18(7):1553. doi: 10.3390/ijms18071553. Int J Mol Sci. 2017. PMID: 28726718 Free PMC article.

9

Metabolism and Bioactivation: It's Time to Expect the Unexpected.

Driscoll JP, Sadlowski CM, Shah NR, Feula A. Driscoll JP, et al. J Med Chem. 2020 Jun 25;63(12):6303-6314. doi: 10.1021/acs.jmedchem.0c00026. Epub 2020 Apr 21. J Med Chem. 2020. PMID: 32267691

10

Elucidating the Mechanism of Tofacitinib Oxidative Decyanation.

Le H, Fan PW, Wong S, Ma S, Driscoll JP, Hop CE, Cyrus Khojasteh S. Le H, et al. Among authors: driscoll jp. Drug Metab Lett. 2016;10(2):136-43. doi: 10.2174/1872312810666160427104954. Drug Metab Lett. 2016. PMID: 27117606

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