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Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization.
Mol Cancer. 2014 Dec 11;13:264. doi: 10.1186/1476-4598-13-264.
Mol Cancer. 2014.
PMID: 25496128
Free PMC article.
NaV1.5 Na⁺ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia.
Brisson L, Driffort V, Benoist L, Poet M, Counillon L, Antelmi E, Rubino R, Besson P, Labbal F, Chevalier S, Reshkin SJ, Gore J, Roger S.
Brisson L, et al. Among authors: driffort v.
J Cell Sci. 2013 Nov 1;126(Pt 21):4835-42. doi: 10.1242/jcs.123901. Epub 2013 Jul 31.
J Cell Sci. 2013.
PMID: 23902689
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How do voltage-gated sodium channels enhance migration and invasiveness in cancer cells?
Besson P, Driffort V, Bon É, Gradek F, Chevalier S, Roger S.
Besson P, et al. Among authors: driffort v.
Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2493-501. doi: 10.1016/j.bbamem.2015.04.013. Epub 2015 Apr 25.
Biochim Biophys Acta. 2015.
PMID: 25922224
Free article.
Review.
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SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer.
Bon E, Driffort V, Gradek F, Martinez-Caceres C, Anchelin M, Pelegrin P, Cayuela ML, Marionneau-Lambot S, Oullier T, Guibon R, Fromont G, Gutierrez-Pajares JL, Domingo I, Piver E, Moreau A, Burlaud-Gaillard J, Frank PG, Chevalier S, Besson P, Roger S.
Bon E, et al. Among authors: driffort v.
Nat Commun. 2016 Dec 5;7:13648. doi: 10.1038/ncomms13648.
Nat Commun. 2016.
PMID: 27917859
Free PMC article.
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Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.
Dutta S, Lopez Charcas O, Tanner S, Gradek F, Driffort V, Roger S, Selander K, Velu SE, Brouillette W.
Dutta S, et al. Among authors: driffort v.
Bioorg Med Chem. 2018 May 15;26(9):2428-2436. doi: 10.1016/j.bmc.2018.04.003. Epub 2018 Apr 3.
Bioorg Med Chem. 2018.
PMID: 29673714
Free PMC article.
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