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Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies.
Easton A, Jensen ML, Wang C, Hagedorn PH, Li Y, Weed M, Meredith JE, Guss V, Jones K, Gill M, Krause C, Brown JM, Hunihan L, Natale J, Fernandes A, Lu Y, Polino J, Bookbinder M, Cadelina G, Benitex Y, Sane R, Morrison J, Drexler D, Mercer SE, Bon C, Pandya NJ, Jagasia R, Ou Yang TH, Distler T, Grüninger F, Meldgaard M, Terrigno M, Macor JE, Albright CF, Loy J, Hoeg AM, Olson RE, Cacace AM. Easton A, et al. Among authors: drexler d. Mol Ther Nucleic Acids. 2022 Aug 4;29:625-642. doi: 10.1016/j.omtn.2022.07.027. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 36090761 Free PMC article.
Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists.
Stazzoni S, Böhmer DFR, Hernichel F, Özdemir D, Pappa A, Drexler D, Bauernfried S, Witte G, Wagner M, Veth S, Hopfner KP, Hornung V, König LM, Carell T. Stazzoni S, et al. Among authors: drexler d. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202207175. doi: 10.1002/anie.202207175. Epub 2022 Aug 31. Angew Chem Int Ed Engl. 2022. PMID: 35876840 Free PMC article.
Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease.
Littau JL, Velilla L, Hase Y, Villalba-Moreno ND, Hagel C, Drexler D, Osorio Restrepo S, Villegas A, Lopera F, Vargas S, Glatzel M, Krasemann S, Quiroz YT, Arboleda-Velasquez JF, Kalaria R, Sepulveda-Falla D. Littau JL, et al. Among authors: drexler d. Brain Pathol. 2022 Nov;32(6):e13097. doi: 10.1111/bpa.13097. Epub 2022 Jun 13. Brain Pathol. 2022. PMID: 35695802 Free PMC article.
Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cth GAMP.
Veth S, Fuchs A, Özdemir D, Dialer C, Drexler DJ, Knechtel F, Witte G, Hopfner KP, Carell T, Ploetz E. Veth S, et al. Among authors: drexler dj. Chembiochem. 2022 Apr 20;23(8):e202200005. doi: 10.1002/cbic.202200005. Epub 2022 Mar 10. Chembiochem. 2022. PMID: 35189023 Free PMC article.
GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile.
Dicker I, Jeffrey JL, Protack T, Lin Z, Cockett M, Chen Y, Sit SY, Gartland M, Meanwell NA, Regueiro-Ren A, Drexler D, Cantone J, McAuliffe B, Krystal M. Dicker I, et al. Among authors: drexler d. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0187621. doi: 10.1128/AAC.01876-21. Epub 2021 Nov 15. Antimicrob Agents Chemother. 2022. PMID: 34780263 Free PMC article.
98 results