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Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study.
Dreier JP, Winkler MKL, Major S, Horst V, Lublinsky S, Kola V, Lemale CL, Kang EJ, Maslarova A, Salur I, Lückl J, Platz J, Jorks D, Oliveira-Ferreira AI, Schoknecht K, Reiffurth C, Milakara D, Wiesenthal D, Hecht N, Dengler NF, Liotta A, Wolf S, Kowoll CM, Schulte AP, Santos E, Güresir E, Unterberg AW, Sarrafzadeh A, Sakowitz OW, Vatter H, Reiner M, Brinker G, Dohmen C, Shelef I, Bohner G, Scheel M, Vajkoczy P, Hartings JA, Friedman A, Martus P, Woitzik J. Dreier JP, et al. Brain. 2022 May 24;145(4):1264-1284. doi: 10.1093/brain/awab457. Brain. 2022. PMID: 35411920 Clinical Trial.
Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia.
Petzold GC, Windmüller O, Haack S, Major S, Buchheim K, Megow D, Gabriel S, Lehmann TN, Drenckhahn C, Peters O, Meierkord H, Heinemann U, Dirnagl U, Dreier JP. Petzold GC, et al. Among authors: dreier jp. Stroke. 2005 Jun;36(6):1270-7. doi: 10.1161/01.STR.0000166023.51307.e0. Epub 2005 May 5. Stroke. 2005. PMID: 15879337
245 results