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Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci.
Menyhárt Á, Frank R, Farkas AE, Süle Z, Varga VÉ, Nyúl-Tóth Á, Meiller A, Ivánkovits-Kiss O, Lemale CL, Szabó Í, Tóth R, Zölei-Szénási D, Woitzik J, Marinesco S, Krizbai IA, Bari F, Dreier JP, Farkas E. Menyhárt Á, et al. Among authors: dreier jp. J Cereb Blood Flow Metab. 2022 Apr;42(4):584-599. doi: 10.1177/0271678X211040056. Epub 2021 Aug 24. J Cereb Blood Flow Metab. 2022. PMID: 34427145 Free PMC article.
Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space.
Dreier JP, Körner K, Ebert N, Görner A, Rubin I, Back T, Lindauer U, Wolf T, Villringer A, Einhäupl KM, Lauritzen M, Dirnagl U. Dreier JP, et al. J Cereb Blood Flow Metab. 1998 Sep;18(9):978-90. doi: 10.1097/00004647-199809000-00007. J Cereb Blood Flow Metab. 1998. PMID: 9740101
Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression.
Oliveira-Ferreira AI, Milakara D, Alam M, Jorks D, Major S, Hartings JA, Lückl J, Martus P, Graf R, Dohmen C, Bohner G, Woitzik J, Dreier JP; COSBID study group. Oliveira-Ferreira AI, et al. Among authors: dreier jp. J Cereb Blood Flow Metab. 2010 Aug;30(8):1504-19. doi: 10.1038/jcbfm.2010.40. Epub 2010 Mar 24. J Cereb Blood Flow Metab. 2010. PMID: 20332797 Free PMC article.
Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage.
Woitzik J, Dreier JP, Hecht N, Fiss I, Sandow N, Major S, Winkler M, Dahlem YA, Manville J, Diepers M, Muench E, Kasuya H, Schmiedek P, Vajkoczy P; COSBID study group. Woitzik J, et al. Among authors: dreier jp. J Cereb Blood Flow Metab. 2012 Feb;32(2):203-12. doi: 10.1038/jcbfm.2011.169. Epub 2011 Dec 7. J Cereb Blood Flow Metab. 2012. PMID: 22146193 Free PMC article.
245 results