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Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology.
de Majo M, Koontz M, Marsan E, Salinas N, Ramsey A, Kuo YM, Seo K, Li H, Dräger N, Leng K, Gonzales SL, Kurnellas M, Miyaoka Y, Klim JR, Kampmann M, Ward ME, Huang EJ, Ullian EM. de Majo M, et al. Among authors: drager n. Stem Cell Reports. 2023 Mar 14;18(3):706-719. doi: 10.1016/j.stemcr.2023.01.012. Epub 2023 Feb 23. Stem Cell Reports. 2023. PMID: 36827976 Free PMC article.
MS4A4A modifies the risk of Alzheimer disease by regulating lipid metabolism and immune response in a unique microglia state.
You SF, Brase L, Filipello F, Iyer AK, Del-Aguila J, He J, D'Oliveira Albanus R, Budde J, Norton J, Gentsch J, Dräger NM, Sattler SM, Kampmann M, Piccio L, Morris JC, Perrin RJ, McDade E; Dominantly Inherited Alzheimer Network; Paul SM, Cashikar AG, Benitez BA, Harari O, Karch CM. You SF, et al. Among authors: drager nm. medRxiv [Preprint]. 2023 Feb 8:2023.02.06.23285545. doi: 10.1101/2023.02.06.23285545. medRxiv. 2023. PMID: 36798226 Free PMC article. Preprint.
A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states.
Dräger NM, Sattler SM, Huang CT, Teter OM, Leng K, Hashemi SH, Hong J, Aviles G, Clelland CD, Zhan L, Udeochu JC, Kodama L, Singleton AB, Nalls MA, Ichida J, Ward ME, Faghri F, Gan L, Kampmann M. Dräger NM, et al. Nat Neurosci. 2022 Sep;25(9):1149-1162. doi: 10.1038/s41593-022-01131-4. Epub 2022 Aug 11. Nat Neurosci. 2022. PMID: 35953545 Free PMC article.
The status of tuberculosis vaccine development.
Schrager LK, Vekemens J, Drager N, Lewinsohn DM, Olesen OF. Schrager LK, et al. Among authors: drager n. Lancet Infect Dis. 2020 Mar;20(3):e28-e37. doi: 10.1016/S1473-3099(19)30625-5. Epub 2020 Jan 31. Lancet Infect Dis. 2020. PMID: 32014117 Review.
TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development.
Kaufmann SHE, Dockrell HM, Drager N, Ho MM, McShane H, Neyrolles O, Ottenhoff THM, Patel B, Roordink D, Spertini F, Stenger S, Thole J, Verreck FAW, Williams A; TBVAC2020 Consortium. Kaufmann SHE, et al. Among authors: drager n. Front Immunol. 2017 Oct 4;8:1203. doi: 10.3389/fimmu.2017.01203. eCollection 2017. Front Immunol. 2017. PMID: 29046674 Free PMC article. Review.
Bin1 directly remodels actin dynamics through its BAR domain.
Dräger NM, Nachman E, Winterhoff M, Brühmann S, Shah P, Katsinelos T, Boulant S, Teleman AA, Faix J, Jahn TR. Dräger NM, et al. EMBO Rep. 2017 Nov;18(11):2051-2066. doi: 10.15252/embr.201744137. Epub 2017 Sep 11. EMBO Rep. 2017. PMID: 28893863 Free PMC article.
37 results