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Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential.
Dejmek M, Šála M, Brazdova A, Vanekova L, Smola M, Klíma M, Břehová P, Buděšínský M, Dračínský M, Procházková E, Zavřel M, Šimák O, Páv O, Boura E, Birkuš G, Nencka R. Dejmek M, et al. Among authors: dracinsky m. Structure. 2022 Aug 4;30(8):1146-1156.e11. doi: 10.1016/j.str.2022.05.012. Epub 2022 Jun 10. Structure. 2022. PMID: 35690061 Free article.
Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.
Krecmerová M, Holý A, Andrei G, Pomeisl K, Tichý T, Brehová P, Masojídková M, Dracínský M, Pohl R, Laflamme G, Naesens L, Hui H, Cihlar T, Neyts J, De Clercq E, Balzarini J, Snoeck R. Krecmerová M, et al. Among authors: dracinsky m. J Med Chem. 2010 Oct 14;53(19):6825-37. doi: 10.1021/jm901828c. J Med Chem. 2010. PMID: 20809641
SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors.
Sála M, De Palma AM, Hřebabecký H, Dejmek M, Dračínský M, Leyssen P, Neyts J, Mertlíková-Kaiserová H, Nencka R. Sála M, et al. Among authors: dracinsky m. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4271-5. doi: 10.1016/j.bmcl.2011.05.070. Epub 2011 May 27. Bioorg Med Chem Lett. 2011. PMID: 21684160
Novel substituted 9-norbornylpurines and their activities against RNA viruses.
Sála M, Hřebabecký H, Leyssen P, Dejmek M, Dračínský M, De Palma AM, Neyts J, Nencka R. Sála M, et al. Among authors: dracinsky m. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1963-8. doi: 10.1016/j.bmcl.2012.01.040. Epub 2012 Jan 25. Bioorg Med Chem Lett. 2012. PMID: 22310228
177 results