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Ivermectin and albendazole coadministration: opportunities for strongyloidiasis control.
Gandasegui J, Onwuchekwa C, Krolewiecki AJ, Doyle SR, Pullan RL, Enbiale W, Kepha S, Hatherell HA, van Lieshout L, Cambra-Pellejà M, Escola V, Muñoz J. Gandasegui J, et al. Among authors: doyle sr. Lancet Infect Dis. 2022 Nov;22(11):e341-e347. doi: 10.1016/S1473-3099(22)00369-3. Epub 2022 Jul 15. Lancet Infect Dis. 2022. PMID: 35850127 Review.
An adaptive phase II/III safety and efficacy randomized controlled trial of single day or three-day fixed-dose albendazole-ivermectin co-formulation versus albendazole for the treatment of Trichuris trichiura and other STH infections. ALIVE trial protocol.
Krolewiecki A, Enbiale W, Gandasegui J, van Lieshout L, Kepha S, Messa Junior A, Bengtson M, Gelaye W, Escola V, Martinez-Valladares M, Cambra-Pellejà M, Algorta J, Martí-Soler H, Fleitas P, Ballester MR, Doyle SR, Williams NA, Legarda A, Mandomando I, Mwandawiro C, Muñoz J. Krolewiecki A, et al. Among authors: doyle sr. Gates Open Res. 2022 May 5;6:62. doi: 10.12688/gatesopenres.13615.1. eCollection 2022. Gates Open Res. 2022. PMID: 36540062 Free PMC article.
The genome of Onchocerca volvulus, agent of river blindness.
Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S. Cotton JA, et al. Among authors: doyle sr. Nat Microbiol. 2016 Nov 21;2:16216. doi: 10.1038/nmicrobiol.2016.216. Nat Microbiol. 2016. PMID: 27869790 Free PMC article.
Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity.
Doyle SR, Bourguinat C, Nana-Djeunga HC, Kengne-Ouafo JA, Pion SDS, Bopda J, Kamgno J, Wanji S, Che H, Kuesel AC, Walker M, Basáñez MG, Boakye DA, Osei-Atweneboana MY, Boussinesq M, Prichard RK, Grant WN. Doyle SR, et al. PLoS Negl Trop Dis. 2017 Jul 26;11(7):e0005816. doi: 10.1371/journal.pntd.0005816. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28746337 Free PMC article.
A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.
Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, Sargison ND. Doyle SR, et al. Genome Biol Evol. 2018 Feb 1;10(2):396-409. doi: 10.1093/gbe/evx269. Genome Biol Evol. 2018. PMID: 29267942 Free PMC article.
Comparative genomics of the major parasitic worms.
International Helminth Genomes Consortium. International Helminth Genomes Consortium. Nat Genet. 2019 Jan;51(1):163-174. doi: 10.1038/s41588-018-0262-1. Epub 2018 Nov 5. Nat Genet. 2019. PMID: 30397333 Free PMC article.
89 results