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Page 1
Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivo.
Busey GW, Manjegowda MC, Huang T, Iobst WH, Naphade SS, Kennedy JA, Doyle CA, Seegren PV, Lynch KR, Desai BN. Busey GW, et al. Among authors: doyle ca. bioRxiv [Preprint]. 2023 Aug 26:2023.05.22.541802. doi: 10.1101/2023.05.22.541802. bioRxiv. 2023. PMID: 37662207 Free PMC article. Preprint.
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, Kuriyan J, Vapalahti O, Balistreri G, Kirchhausen T, Brunger AT. Yang K, et al. Among authors: doyle ca. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2210990119. doi: 10.1073/pnas.2210990119. Epub 2022 Sep 19. Proc Natl Acad Sci U S A. 2022. PMID: 36122200 Free PMC article.
SARS-CoV-2 requires acidic pH to infect cells.
Kreutzberger AJB, Sanyal A, Saminathan A, Bloyet LM, Stumpf S, Liu Z, Ojha R, Patjas MT, Geneid A, Scanavachi G, Doyle CA, Somerville E, Correia RBDC, Di Caprio G, Toppila-Salmi S, Mäkitie A, Kiessling V, Vapalahti O, Whelan SPJ, Balistreri G, Kirchhausen T. Kreutzberger AJB, et al. Among authors: doyle ca. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2209514119. doi: 10.1073/pnas.2209514119. Epub 2022 Sep 1. Proc Natl Acad Sci U S A. 2022. PMID: 36048924 Free PMC article.
Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein.
Yang K, Wang C, Kreutzberger AJB, Ojha R, Kuivanen S, Couoh-Cardel S, Muratcioglu S, Eisen TJ, White KI, Held RG, Subramanian S, Marcus K, Pfuetzner RA, Esquivies L, Doyle CA, Kuriyan J, Vapalahti O, Balistreri G, Kirchhausen T, Brunger AT. Yang K, et al. Among authors: doyle ca. bioRxiv [Preprint]. 2022 Aug 11:2022.08.11.503553. doi: 10.1101/2022.08.11.503553. bioRxiv. 2022. PMID: 35982670 Free PMC article. Updated. Preprint.
SARS-CoV-2 requires acidic pH to infect cells.
Kreutzberger AJB, Sanyal A, Saminathan A, Bloyet LM, Stumpf S, Liu Z, Ojha R, Patjas MT, Geneid A, Scanavachi G, Doyle CA, Somerville E, Bango Da Cunha Correira R, Di Caprio G, Toppila-Salmi S, Mäkitie A, Kiessling V, Vapalahti O, Whelan SPJ, Balistreri G, Kirchhausen T. Kreutzberger AJB, et al. Among authors: doyle ca. bioRxiv [Preprint]. 2022 Jun 14:2022.06.09.495472. doi: 10.1101/2022.06.09.495472. bioRxiv. 2022. PMID: 35702155 Free PMC article. Updated. Preprint.
In Response.
Malinzak EB, Hertzberg LB, Doyle CA, Flood P, Kraus MB, Rebello E, Pai SL, Pease S. Malinzak EB, et al. Among authors: doyle ca. Anesth Analg. 2022 Apr 1;134(4):e23-e24. doi: 10.1213/ANE.0000000000005914. Anesth Analg. 2022. PMID: 35299224 No abstract available.
59 results