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XPO1 inhibition sensitises CLL cells to NK cell mediated cytotoxicity and overcomes HLA-E expression.
Leukemia. 2023 Oct;37(10):2036-2049. doi: 10.1038/s41375-023-01984-z. Epub 2023 Aug 1.
Leukemia. 2023.
PMID: 37528310
Free PMC article.
Selinexor Enhances NK Cell Activation Against Malignant B Cells via Downregulation of HLA-E.
Fisher JG, Walker CJ, Doyle AD, Johnson PW, Forconi F, Cragg MS, Landesman Y, Khakoo SI, Blunt MD.
Fisher JG, et al.
Front Oncol. 2021 Dec 1;11:785635. doi: 10.3389/fonc.2021.785635. eCollection 2021.
Front Oncol. 2021.
PMID: 34926302
Free PMC article.
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KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.
Blunt MD, Vallejo Pulido A, Fisher JG, Graham LV, Doyle ADP, Fulton R, Carter MJ, Polak M, Johnson PWM, Cragg MS, Forconi F, Khakoo SI.
Blunt MD, et al. Among authors: doyle adp.
J Immunol. 2022 Jul 15;209(2):379-390. doi: 10.4049/jimmunol.2101139. Epub 2022 Jun 29.
J Immunol. 2022.
PMID: 35768150
Free PMC article.
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Disruption of the NKG2A:HLA-E Immune Checkpoint Axis to Enhance NK Cell Activation against Cancer.
Fisher JG, Doyle ADP, Graham LV, Khakoo SI, Blunt MD.
Fisher JG, et al. Among authors: doyle adp.
Vaccines (Basel). 2022 Nov 23;10(12):1993. doi: 10.3390/vaccines10121993.
Vaccines (Basel). 2022.
PMID: 36560403
Free PMC article.
Review.
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