Downward J - Search Results

1

Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance.

Castellano E, Sheridan C, Thin MZ, Nye E, Spencer-Dene B, Diefenbacher ME, Moore C, Kumar MS, Murillo MM, Grönroos E, Lassailly F, Stamp G, Downward J. Castellano E, et al. Among authors: downward j. Cancer Cell. 2013 Nov 11;24(5):617-30. doi: 10.1016/j.ccr.2013.09.012. Cancer Cell. 2013. PMID: 24229709 Free PMC article.

2

The activation of phosphatidylinositol 3-kinase by Ras.

Kodaki T, Woscholski R, Hallberg B, Rodriguez-Viciana P, Downward J, Parker PJ. Kodaki T, et al. Among authors: downward j. Curr Biol. 1994 Sep 1;4(9):798-806. doi: 10.1016/s0960-9822(00)00177-9. Curr Biol. 1994. PMID: 7820549

3

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor.

Buday L, Downward J. Buday L, et al. Among authors: downward j. Cell. 1993 May 7;73(3):611-20. doi: 10.1016/0092-8674(93)90146-h. Cell. 1993. PMID: 8490966

4

KSR: a novel player in the RAS pathway.

Downward J. Downward J. Cell. 1995 Dec 15;83(6):831-4. doi: 10.1016/0092-8674(95)90198-1. Cell. 1995. PMID: 8521506 Free article. Review. No abstract available.

5

Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation.

Rodriguez-Viciana P, Warne PH, Vanhaesebroeck B, Waterfield MD, Downward J. Rodriguez-Viciana P, et al. Among authors: downward j. EMBO J. 1996 May 15;15(10):2442-51. EMBO J. 1996. PMID: 8665852 Free PMC article.

6

Control of ras activation.

Downward J. Downward J. Cancer Surv. 1996;27:87-100. Cancer Surv. 1996. PMID: 8909796 Review.

7

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras.

Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A, Downward J. Rodriguez-Viciana P, et al. Among authors: downward j. Cell. 1997 May 2;89(3):457-67. doi: 10.1016/s0092-8674(00)80226-3. Cell. 1997. PMID: 9150145 Free article.

8

Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells.

Khwaja A, Downward J. Khwaja A, et al. Among authors: downward j. J Cell Biol. 1997 Nov 17;139(4):1017-23. doi: 10.1083/jcb.139.4.1017. J Cell Biol. 1997. PMID: 9362519 Free PMC article.

9

Targeting RAS signalling pathways in cancer therapy.

Downward J. Downward J. Nat Rev Cancer. 2003 Jan;3(1):11-22. doi: 10.1038/nrc969. Nat Rev Cancer. 2003. PMID: 12509763 Review.

10

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component.

Schulze A, Nicke B, Warne PH, Tomlinson S, Downward J. Schulze A, et al. Among authors: downward j. Mol Biol Cell. 2004 Jul;15(7):3450-63. doi: 10.1091/mbc.e03-11-0807. Epub 2004 Apr 16. Mol Biol Cell. 2004. PMID: 15090615 Free PMC article.

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