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Role of RAS in the regulation of PI 3-kinase.
Castellano E, Downward J. Castellano E, et al. Among authors: downward j. Curr Top Microbiol Immunol. 2010;346:143-69. doi: 10.1007/82_2010_56. Curr Top Microbiol Immunol. 2010. PMID: 20563706 Review.
PI3K pathway dependencies in endometrioid endometrial cancer cell lines.
Weigelt B, Warne PH, Lambros MB, Reis-Filho JS, Downward J. Weigelt B, et al. Among authors: downward j. Clin Cancer Res. 2013 Jul 1;19(13):3533-44. doi: 10.1158/1078-0432.CCR-12-3815. Epub 2013 May 14. Clin Cancer Res. 2013. PMID: 23674493 Free PMC article.
Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance.
Castellano E, Sheridan C, Thin MZ, Nye E, Spencer-Dene B, Diefenbacher ME, Moore C, Kumar MS, Murillo MM, Grönroos E, Lassailly F, Stamp G, Downward J. Castellano E, et al. Among authors: downward j. Cancer Cell. 2013 Nov 11;24(5):617-30. doi: 10.1016/j.ccr.2013.09.012. Cancer Cell. 2013. PMID: 24229709 Free PMC article.
Inhibiting the RAS-PI3K pathway in cancer therapy.
Sheridan C, Downward J. Sheridan C, et al. Among authors: downward j. Enzymes. 2013;34 Pt. B:107-36. doi: 10.1016/B978-0-12-420146-0.00005-6. Epub 2013 Nov 7. Enzymes. 2013. PMID: 25034102 Review.
Tumour-suppression function of KLF12 through regulation of anoikis.
Godin-Heymann N, Brabetz S, Murillo MM, Saponaro M, Santos CR, Lobley A, East P, Chakravarty P, Matthews N, Kelly G, Jordan S, Castellano E, Downward J. Godin-Heymann N, et al. Among authors: downward j. Oncogene. 2016 Jun 23;35(25):3324-34. doi: 10.1038/onc.2015.394. Epub 2015 Oct 12. Oncogene. 2016. PMID: 26455320 Free PMC article.
296 results