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Cancer and the bromodomains of BAF180.
Brownlee PM, Chambers AL, Oliver AW, Downs JA. Brownlee PM, et al. Among authors: downs ja. Biochem Soc Trans. 2012 Apr;40(2):364-9. doi: 10.1042/BST20110754. Biochem Soc Trans. 2012. PMID: 22435813 Review.
Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
Myrianthopoulos V, Gaboriaud-Kolar N, Tallant C, Hall ML, Grigoriou S, Brownlee PM, Fedorov O, Rogers C, Heidenreich D, Wanior M, Drosos N, Mexia N, Savitsky P, Bagratuni T, Kastritis E, Terpos E, Filippakopoulos P, Müller S, Skaltsounis AL, Downs JA, Knapp S, Mikros E. Myrianthopoulos V, et al. Among authors: downs ja. J Med Chem. 2016 Oct 13;59(19):8787-8803. doi: 10.1021/acs.jmedchem.6b00355. Epub 2016 Sep 27. J Med Chem. 2016. PMID: 27617704 Free PMC article.
The BAH domain of Rsc2 is a histone H3 binding domain.
Chambers AL, Pearl LH, Oliver AW, Downs JA. Chambers AL, et al. Among authors: downs ja. Nucleic Acids Res. 2013 Oct;41(19):9168-82. doi: 10.1093/nar/gkt662. Epub 2013 Jul 31. Nucleic Acids Res. 2013. PMID: 23907388 Free PMC article.
A role for chromatin remodellers in replication of damaged DNA.
Niimi A, Chambers AL, Downs JA, Lehmann AR. Niimi A, et al. Among authors: downs ja. Nucleic Acids Res. 2012 Aug;40(15):7393-403. doi: 10.1093/nar/gks453. Epub 2012 May 25. Nucleic Acids Res. 2012. PMID: 22638582 Free PMC article.
154 results