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Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications.
Meade BR, Gogoi K, Hamil AS, Palm-Apergi C, van den Berg A, Hagopian JC, Springer AD, Eguchi A, Kacsinta AD, Dowdy CF, Presente A, Lönn P, Kaulich M, Yoshioka N, Gros E, Cui XS, Dowdy SF. Meade BR, et al. Among authors: dowdy cf, dowdy sf. Nat Biotechnol. 2014 Dec;32(12):1256-61. doi: 10.1038/nbt.3078. Epub 2014 Nov 17. Nat Biotechnol. 2014. PMID: 25402614 Free PMC article.
Overcoming delivery barriers with LNPs.
Jadhav SG, Dowdy SF. Jadhav SG, et al. Among authors: dowdy sf. Nat Mater. 2021 May;20(5):575-577. doi: 10.1038/s41563-021-00988-3. Nat Mater. 2021. PMID: 33911220 No abstract available.
Delivery of RNA Therapeutics: The Great Endosomal Escape!
Dowdy SF, Setten RL, Cui XS, Jadhav SG. Dowdy SF, et al. Nucleic Acid Ther. 2022 Oct;32(5):361-368. doi: 10.1089/nat.2022.0004. Epub 2022 May 24. Nucleic Acid Ther. 2022. PMID: 35612432 Free PMC article. Review.
Induction of RNAi Responses by Short Left-Handed Hairpin RNAi Triggers.
Hagopian JC, Hamil AS, van den Berg A, Meade BR, Eguchi A, Palm-Apergi C, Dowdy SF. Hagopian JC, et al. Among authors: dowdy sf. Nucleic Acid Ther. 2017 Oct;27(5):260-271. doi: 10.1089/nat.2017.0686. Epub 2017 Sep 21. Nucleic Acid Ther. 2017. PMID: 28933656 Free PMC article.
138 results