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Deciphering the tumour immune microenvironment cell by cell.
Nabhan M, Egan D, Kreileder M, Zhernovkov V, Timosenko E, Slidel T, Dovedi S, Glennon K, Brennan D, Kolch W. Nabhan M, et al. Immunooncol Technol. 2023 Apr 7;18:100383. doi: 10.1016/j.iotech.2023.100383. eCollection 2023 Jun. Immunooncol Technol. 2023. PMID: 37234284 Free PMC article. Review.
Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity.
Lee CYC, Kennedy BC, Richoz N, Dean I, Tuong ZK, Gaspal F, Li Z, Willis C, Hasegawa T, Whiteside SK, Posner DA, Carlesso G, Hammond SA, Dovedi SJ, Roychoudhuri R, Withers DR, Clatworthy MR. Lee CYC, et al. Among authors: dovedi sj. Nat Commun. 2024 Jan 24;15(1):682. doi: 10.1038/s41467-024-44787-1. Nat Commun. 2024. PMID: 38267413 Free PMC article.
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity.
Dean I, Lee CYC, Tuong ZK, Li Z, Tibbitt CA, Willis C, Gaspal F, Kennedy BC, Matei-Rascu V, Fiancette R, Nordenvall C, Lindforss U, Baker SM, Stockmann C, Sexl V, Hammond SA, Dovedi SJ, Mjösberg J, Hepworth MR, Carlesso G, Clatworthy MR, Withers DR. Dean I, et al. Among authors: dovedi sj. Nat Commun. 2024 Jan 24;15(1):683. doi: 10.1038/s41467-024-44789-z. Nat Commun. 2024. PMID: 38267402 Free PMC article.
Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Graziano V, Dannhorn A, Hulme H, Williamson K, Buckley H, Karim SA, Wilson M, Lee SY, Kaistha BP, Islam S, Thaventhiran JED, Richards FM, Goodwin R, Brais R, Morton JP, Dovedi SJ, Schuller AG, Eyles J, Jodrell DI. Graziano V, et al. Among authors: dovedi sj. J Immunother Cancer. 2023 Aug;11(8):e006457. doi: 10.1136/jitc-2022-006457. J Immunother Cancer. 2023. PMID: 37553182 Free PMC article.
Small Gene Networks Delineate Immune Cell States and Characterize Immunotherapy Response in Melanoma.
Egan D, Kreileder M, Nabhan M, Iglesias-Martinez LF, Dovedi SJ, Valge-Archer V, Grover A, Wilkinson RW, Slidel T, Bendtsen C, Barrett IP, Brennan DJ, Kolch W, Zhernovkov V. Egan D, et al. Among authors: dovedi sj. Cancer Immunol Res. 2023 Aug 3;11(8):1125-1136. doi: 10.1158/2326-6066.CIR-22-0563. Cancer Immunol Res. 2023. PMID: 37229623 Free PMC article.
50 results