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The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth.
Dong L, Chen C, Zhang Y, Guo P, Wang Z, Li J, Liu Y, Liu J, Chang R, Li Y, Liang G, Lai W, Sun M, Dougherty U, Bissonnette MB, Wang H, Shen L, Xu MM, Han D. Dong L, et al. Among authors: dougherty u. Cancer Cell. 2021 Jul 12;39(7):945-957.e10. doi: 10.1016/j.ccell.2021.04.016. Epub 2021 May 20. Cancer Cell. 2021. PMID: 34019807 Free article.
Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci.
Cohen G, Mustafi R, Chumsangsri A, Little N, Nathanson J, Cerda S, Jagadeeswaran S, Dougherty U, Joseph L, Hart J, Yerian L, Tretiakova M, Yuan W, Obara P, Khare S, Sinicrope FA, Fichera A, Boss GR, Carroll R, Bissonnette M. Cohen G, et al. Among authors: dougherty u. Cancer Res. 2006 Jun 1;66(11):5656-64. doi: 10.1158/0008-5472.CAN-05-0308. Cancer Res. 2006. PMID: 16740703
Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.
Fichera A, Little N, Jagadeeswaran S, Dougherty U, Sehdev A, Mustafi R, Cerda S, Yuan W, Khare S, Tretiakova M, Gong C, Tallerico M, Cohen G, Joseph L, Hart J, Turner JR, Bissonnette M. Fichera A, et al. Among authors: dougherty u. Cancer Res. 2007 Jan 15;67(2):827-35. doi: 10.1158/0008-5472.CAN-05-3343. Cancer Res. 2007. PMID: 17234795 Free PMC article.
The renin-angiotensin system mediates EGF receptor-vitamin d receptor cross-talk in colitis-associated colon cancer.
Dougherty U, Mustafi R, Sadiq F, Almoghrabi A, Mustafi D, Kreisheh M, Sundaramurthy S, Liu W, Konda VJ, Pekow J, Khare S, Hart J, Joseph L, Wyrwicz A, Karczmar GS, Li YC, Bissonnette M. Dougherty U, et al. Clin Cancer Res. 2014 Nov 15;20(22):5848-5859. doi: 10.1158/1078-0432.CCR-14-0209. Epub 2014 Sep 11. Clin Cancer Res. 2014. PMID: 25212605 Free PMC article.
The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon.
Grimm WA, Messer JS, Murphy SF, Nero T, Lodolce JP, Weber CR, Logsdon MF, Bartulis S, Sylvester BE, Springer A, Dougherty U, Niewold TB, Kupfer SS, Ellis N, Huo D, Bissonnette M, Boone DL. Grimm WA, et al. Among authors: dougherty u. Gut. 2016 Mar;65(3):456-64. doi: 10.1136/gutjnl-2014-308735. Epub 2015 Feb 2. Gut. 2016. PMID: 25645662 Free PMC article.
ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer.
Mustafi R, Dougherty U, Mustafi D, Ayaloglu-Butun F, Fletcher M, Adhikari S, Sadiq F, Meckel K, Haider HI, Khalil A, Pekow J, Konda V, Joseph L, Hart J, Fichera A, Li YC, Bissonnette M. Mustafi R, et al. Among authors: dougherty u. Clin Cancer Res. 2017 Jan 15;23(2):549-561. doi: 10.1158/1078-0432.CCR-15-3140. Epub 2016 Aug 3. Clin Cancer Res. 2017. PMID: 27489286 Free PMC article.
miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD.
Pekow J, Meckel K, Dougherty U, Huang Y, Chen X, Almoghrabi A, Mustafi R, Ayaloglu-Butun F, Deng Z, Haider HI, Hart J, Rubin DT, Kwon JH, Bissonnette M. Pekow J, et al. Among authors: dougherty u. Clin Cancer Res. 2017 Sep 1;23(17):5281-5291. doi: 10.1158/1078-0432.CCR-17-0171. Epub 2017 Jun 9. Clin Cancer Res. 2017. PMID: 28600480 Free PMC article.
41 results