Dougherty PM - Search Results

1

Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors.

Tavares-Ferreira D, Shiers S, Ray PR, Wangzhou A, Jeevakumar V, Sankaranarayanan I, Cervantes AM, Reese JC, Chamessian A, Copits BA, Dougherty PM, Gereau RW 4th, Burton MD, Dussor G, Price TJ. Tavares-Ferreira D, et al. Among authors: dougherty pm. Sci Transl Med. 2022 Feb 16;14(632):eabj8186. doi: 10.1126/scitranslmed.abj8186. Epub 2022 Feb 16. Sci Transl Med. 2022. PMID: 35171654 Free PMC article.

2

Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy.

Zhang H, Dougherty PM. Zhang H, et al. Among authors: dougherty pm. Anesthesiology. 2014 Jun;120(6):1463-75. doi: 10.1097/ALN.0000000000000176. Anesthesiology. 2014. PMID: 24534904 Free PMC article.

3

Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy.

Li Y, Tatsui CE, Rhines LD, North RY, Harrison DS, Cassidy RM, Johansson CA, Kosturakis AK, Edwards DD, Zhang H, Dougherty PM. Li Y, et al. Among authors: dougherty pm. Pain. 2017 Mar;158(3):417-429. doi: 10.1097/j.pain.0000000000000774. Pain. 2017. PMID: 27902567 Free PMC article.

4

Nociceptor Translational Profiling Reveals the Ragulator-Rag GTPase Complex as a Critical Generator of Neuropathic Pain.

Megat S, Ray PR, Moy JK, Lou TF, Barragán-Iglesias P, Li Y, Pradhan G, Wanghzou A, Ahmad A, Burton MD, North RY, Dougherty PM, Khoutorsky A, Sonenberg N, Webster KR, Dussor G, Campbell ZT, Price TJ. Megat S, et al. Among authors: dougherty pm. J Neurosci. 2019 Jan 16;39(3):393-411. doi: 10.1523/JNEUROSCI.2661-18.2018. Epub 2018 Nov 20. J Neurosci. 2019. PMID: 30459229 Free PMC article.

5

Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons.

North RY, Li Y, Ray P, Rhines LD, Tatsui CE, Rao G, Johansson CA, Zhang H, Kim YH, Zhang B, Dussor G, Kim TH, Price TJ, Dougherty PM. North RY, et al. Among authors: dougherty pm. Brain. 2019 May 1;142(5):1215-1226. doi: 10.1093/brain/awz063. Brain. 2019. PMID: 30887021 Free PMC article.

6

ACE2 and SCARF expression in human dorsal root ganglion nociceptors: implications for SARS-CoV-2 virus neurological effects.

Shiers S, Ray PR, Wangzhou A, Sankaranarayanan I, Tatsui CE, Rhines LD, Li Y, Uhelski ML, Dougherty PM, Price TJ. Shiers S, et al. Among authors: dougherty pm. Pain. 2020 Nov;161(11):2494-2501. doi: 10.1097/j.pain.0000000000002051. Pain. 2020. PMID: 32826754 Free PMC article.

7

Human cells and networks of pain: Transforming pain target identification and therapeutic development.

Renthal W, Chamessian A, Curatolo M, Davidson S, Burton M, Dib-Hajj S, Dougherty PM, Ebert AD, Gereau RW 4th, Ghetti A, Gold MS, Hoben G, Menichella DM, Mercier P, Ray WZ, Salvemini D, Seal RP, Waxman S, Woolf CJ, Stucky CL, Price TJ. Renthal W, et al. Among authors: dougherty pm. Neuron. 2021 May 5;109(9):1426-1429. doi: 10.1016/j.neuron.2021.04.005. Neuron. 2021. PMID: 33957072 Free PMC article.

8

Studying human nociceptors: from fundamentals to clinic.

Middleton SJ, Barry AM, Comini M, Li Y, Ray PR, Shiers S, Themistocleous AC, Uhelski ML, Yang X, Dougherty PM, Price TJ, Bennett DL. Middleton SJ, et al. Among authors: dougherty pm. Brain. 2021 Jun 22;144(5):1312-1335. doi: 10.1093/brain/awab048. Brain. 2021. PMID: 34128530 Free PMC article. Review.

9

Electrophysiological Alterations Driving Pain-Associated Spontaneous Activity in Human Sensory Neuron Somata Parallel Alterations Described in Spontaneously Active Rodent Nociceptors.

North RY, Odem MA, Li Y, Tatsui CE, Cassidy RM, Dougherty PM, Walters ET. North RY, et al. Among authors: dougherty pm. J Pain. 2022 Aug;23(8):1343-1357. doi: 10.1016/j.jpain.2022.02.009. Epub 2022 Mar 12. J Pain. 2022. PMID: 35292377 Free PMC article.

10

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain.

Ray PR, Shiers S, Caruso JP, Tavares-Ferreira D, Sankaranarayanan I, Uhelski ML, Li Y, North RY, Tatsui C, Dussor G, Burton MD, Dougherty PM, Price TJ. Ray PR, et al. Among authors: dougherty pm. Brain. 2023 Feb 13;146(2):749-766. doi: 10.1093/brain/awac266. Brain. 2023. PMID: 35867896 Free PMC article.

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