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A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.
Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert TF, Ploss A, Carbone A, Cosset FL, Lavillette D. Douam F, et al. PLoS Pathog. 2018 Mar 5;14(3):e1006908. doi: 10.1371/journal.ppat.1006908. eCollection 2018 Mar. PLoS Pathog. 2018. PMID: 29505618 Free PMC article.
The antimalarial ferroquine is an inhibitor of hepatitis C virus.
Vausselin T, Calland N, Belouzard S, Descamps V, Douam F, Helle F, François C, Lavillette D, Duverlie G, Wahid A, Fénéant L, Cocquerel L, Guérardel Y, Wychowski C, Biot C, Dubuisson J. Vausselin T, et al. Among authors: douam f. Hepatology. 2013 Jul;58(1):86-97. doi: 10.1002/hep.26273. Epub 2013 May 14. Hepatology. 2013. PMID: 23348596 Free PMC article.
Up-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.
Bocchetta S, Maillard P, Yamamoto M, Gondeau C, Douam F, Lebreton S, Lagaye S, Pol S, Helle F, Plengpanich W, Guérin M, Bourgine M, Michel ML, Lavillette D, Roingeard P, le Goff W, Budkowska A. Bocchetta S, et al. Among authors: douam f. PLoS One. 2014 Mar 19;9(3):e92140. doi: 10.1371/journal.pone.0092140. eCollection 2014. PLoS One. 2014. PMID: 24646941 Free PMC article.
The mechanism of HCV entry into host cells.
Douam F, Lavillette D, Cosset FL. Douam F, et al. Prog Mol Biol Transl Sci. 2015;129:63-107. doi: 10.1016/bs.pmbts.2014.10.003. Epub 2014 Dec 12. Prog Mol Biol Transl Sci. 2015. PMID: 25595801 Review.
New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A.
Fénéant L, Potel J, François C, Sané F, Douam F, Belouzard S, Calland N, Vausselin T, Rouillé Y, Descamps V, Baumert TF, Duverlie G, Lavillette D, Hober D, Dubuisson J, Wychowski C, Cocquerel L. Fénéant L, et al. Among authors: douam f. J Virol. 2015 Aug;89(16):8346-64. doi: 10.1128/JVI.00192-15. Epub 2015 Jun 3. J Virol. 2015. PMID: 26041282 Free PMC article.
42 results