Dotto GP - Search Results

1

Sphingolipids control dermal fibroblast heterogeneity.

Capolupo L, Khven I, Lederer AR, Mazzeo L, Glousker G, Ho S, Russo F, Montoya JP, Bhandari DR, Bowman AP, Ellis SR, Guiet R, Burri O, Detzner J, Muthing J, Homicsko K, Kuonen F, Gilliet M, Spengler B, Heeren RMA, Dotto GP, La Manno G, D'Angelo G. Capolupo L, et al. Among authors: dotto gp. Science. 2022 Apr 15;376(6590):eabh1623. doi: 10.1126/science.abh1623. Epub 2022 Apr 15. Science. 2022. PMID: 35420948

2

Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation.

Clocchiatti A, Ghosh S, Procopio MG, Mazzeo L, Bordignon P, Ostano P, Goruppi S, Bottoni G, Katarkar A, Levesque M, Kölblinger P, Dummer R, Neel V, Özdemir BC, Dotto GP. Clocchiatti A, et al. Among authors: dotto gp. J Clin Invest. 2018 Dec 3;128(12):5531-5548. doi: 10.1172/JCI99159. Epub 2018 Nov 5. J Clin Invest. 2018. PMID: 30395538 Free PMC article.

3

Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis.

Ma M, Ghosh S, Tavernari D, Katarkar A, Clocchiatti A, Mazzeo L, Samarkina A, Epiney J, Yu YR, Ho PC, Levesque MP, Özdemir BC, Ciriello G, Dummer R, Dotto GP. Ma M, et al. Among authors: dotto gp. J Exp Med. 2021 Feb 1;218(2):e20201137. doi: 10.1084/jem.20201137. J Exp Med. 2021. PMID: 33112375 Free PMC article.

4

ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.

Mazzeo L, Ghosh S, Di Cicco E, Isma J, Tavernari D, Samarkina A, Ostano P, Youssef MK, Simon C, Dotto GP. Mazzeo L, et al. Among authors: dotto gp. Nat Commun. 2024 Feb 3;15(1):1038. doi: 10.1038/s41467-024-45308-w. Nat Commun. 2024. PMID: 38310103 Free PMC article.

5

Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control.

Di Cunto F, Topley G, Calautti E, Hsiao J, Ong L, Seth PK, Dotto GP. Di Cunto F, et al. Among authors: dotto gp. Science. 1998 May 15;280(5366):1069-72. doi: 10.1126/science.280.5366.1069. Science. 1998. PMID: 9582119

6

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation.

Procopio MG, Laszlo C, Al Labban D, Kim DE, Bordignon P, Jo SH, Goruppi S, Menietti E, Ostano P, Ala U, Provero P, Hoetzenecker W, Neel V, Kilarski WW, Swartz MA, Brisken C, Lefort K, Dotto GP. Procopio MG, et al. Among authors: dotto gp. Nat Cell Biol. 2015 Sep;17(9):1193-204. doi: 10.1038/ncb3228. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302407 Free PMC article.

7

PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation.

Jo SH, Kim DE, Clocchiatti A, Dotto GP. Jo SH, et al. Among authors: dotto gp. Oncotarget. 2016 Sep 13;7(37):58717-58727. doi: 10.18632/oncotarget.11227. Oncotarget. 2016. PMID: 27542230 Free PMC article.

8

Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation.

Kim DE, Procopio MG, Ghosh S, Jo SH, Goruppi S, Magliozzi F, Bordignon P, Neel V, Angelino P, Dotto GP. Kim DE, et al. Among authors: dotto gp. J Exp Med. 2017 Aug 7;214(8):2349-2368. doi: 10.1084/jem.20170724. Epub 2017 Jul 6. J Exp Med. 2017. PMID: 28684431 Free PMC article.

9

The ULK3 Kinase Is Critical for Convergent Control of Cancer-Associated Fibroblast Activation by CSL and GLI.

Goruppi S, Procopio MG, Jo S, Clocchiatti A, Neel V, Dotto GP. Goruppi S, et al. Among authors: dotto gp. Cell Rep. 2017 Sep 5;20(10):2468-2479. doi: 10.1016/j.celrep.2017.08.048. Cell Rep. 2017. PMID: 28877478 Free PMC article.

10

Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant.

Bordignon P, Bottoni G, Xu X, Popescu AS, Truan Z, Guenova E, Kofler L, Jafari P, Ostano P, Röcken M, Neel V, Dotto GP. Bordignon P, et al. Among authors: dotto gp. Cell Rep. 2019 Aug 27;28(9):2358-2372.e6. doi: 10.1016/j.celrep.2019.07.092. Cell Rep. 2019. PMID: 31461652 Free PMC article.

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