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ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.
Blackwood EA, Hofmann C, Santo Domingo M, Bilal AS, Sarakki A, Stauffer W, Arrieta A, Thuerauf DJ, Kolkhorst FW, Müller OJ, Jakobi T, Dieterich C, Katus HA, Doroudgar S, Glembotski CC. Blackwood EA, et al. Among authors: doroudgar s. Circ Res. 2019 Jan 4;124(1):79-93. doi: 10.1161/CIRCRESAHA.118.313854. Circ Res. 2019. PMID: 30582446 Free PMC article.
Mesencephalic astrocyte-derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart.
Arrieta A, Blackwood EA, Stauffer WT, Santo Domingo M, Bilal AS, Thuerauf DJ, Pentoney AN, Aivati C, Sarakki AV, Doroudgar S, Glembotski CC. Arrieta A, et al. Among authors: doroudgar s. J Biol Chem. 2020 May 29;295(22):7566-7583. doi: 10.1074/jbc.RA120.013345. Epub 2020 Apr 23. J Biol Chem. 2020. PMID: 32327487 Free PMC article.
Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response.
Blackwood EA, Thuerauf DJ, Stastna M, Stephens H, Sand Z, Pentoney A, Azizi K, Jakobi T, Van Eyk JE, Katus HA, Glembotski CC, Doroudgar S. Blackwood EA, et al. Among authors: doroudgar s. J Mol Cell Cardiol. 2020 Jun;143:132-144. doi: 10.1016/j.yjmcc.2020.04.012. Epub 2020 Apr 25. J Mol Cell Cardiol. 2020. PMID: 32339566 Free PMC article.
S100A4 protects the myocardium against ischemic stress.
Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla FG, Casillas A, Nguyen K, Gude N, Toko H, Ornelas L, Thuerauf DJ, Glembotski CC, Sussman MA, Völkers M. Doroudgar S, et al. J Mol Cell Cardiol. 2016 Nov;100:54-63. doi: 10.1016/j.yjmcc.2016.10.001. Epub 2016 Oct 6. J Mol Cell Cardiol. 2016. PMID: 27721024 Free PMC article.
Protein Misfolding in Cardiac Disease.
Hofmann C, Katus HA, Doroudgar S. Hofmann C, et al. Among authors: doroudgar s. Circulation. 2019 Apr 30;139(18):2085-2088. doi: 10.1161/CIRCULATIONAHA.118.037417. Circulation. 2019. PMID: 31034286 Review. No abstract available.
Monitoring Cell-Type-Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress.
Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann C, Jürgensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi F, Friedrich UA, Mauz V, Backs J, Kramer G, Katus HA, Dieterich C, Völkers M. Doroudgar S, et al. Circ Res. 2019 Aug 2;125(4):431-448. doi: 10.1161/CIRCRESAHA.119.314817. Epub 2019 Jul 9. Circ Res. 2019. PMID: 31284834 Free PMC article.
mTORC1 inhibition impairs activation of the unfolded protein response and induces cell death during ER stress in cardiomyocytes.
Hofmann C, Löwenthal Z, Aghajani M, Kaufman RJ, Katus HA, Frey N, Glembotski CC, Völkers M, Doroudgar S. Hofmann C, et al. Among authors: doroudgar s. Am J Physiol Heart Circ Physiol. 2023 Aug 1;325(2):H311-H320. doi: 10.1152/ajpheart.00682.2022. Epub 2023 Jun 9. Am J Physiol Heart Circ Physiol. 2023. PMID: 37294892 Free PMC article.
67 results