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Development of an antibody cocktail for treatment of Sudan virus infection.
Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3768-3778. doi: 10.1073/pnas.1914985117. Epub 2020 Feb 3.
Proc Natl Acad Sci U S A. 2020.
PMID: 32015126
Free PMC article.
Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2.
Chan KK, Dorosky D, Sharma P, Abbasi SA, Dye JM, Kranz DM, Herbert AS, Procko E.
Chan KK, et al.
Science. 2020 Sep 4;369(6508):1261-1265. doi: 10.1126/science.abc0870. Epub 2020 Aug 4.
Science. 2020.
PMID: 32753553
Free PMC article.
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BIKE regulates dengue virus infection and is a cellular target for broad-spectrum antivirals.
Pu S, Schor S, Karim M, Saul S, Robinson M, Kumar S, Prugar LI, Dorosky DE, Brannan J, Dye JM, Einav S.
Pu S, et al. Among authors: dorosky de.
Antiviral Res. 2020 Dec;184:104966. doi: 10.1016/j.antiviral.2020.104966. Epub 2020 Nov 1.
Antiviral Res. 2020.
PMID: 33137362
Free PMC article.
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Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity.
Verdonck S, Pu SY, Sorrell FJ, Elkins JM, Froeyen M, Gao LJ, Prugar LI, Dorosky DE, Brannan JM, Barouch-Bentov R, Knapp S, Dye JM, Herdewijn P, Einav S, De Jonghe S.
Verdonck S, et al. Among authors: dorosky de.
J Med Chem. 2019 Jun 27;62(12):5810-5831. doi: 10.1021/acs.jmedchem.9b00136. Epub 2019 Jun 12.
J Med Chem. 2019.
PMID: 31136173
Free PMC article.
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Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates.
Sakai S, Lora NE, Kauffman KD, Dorosky DE, Oh S, Namasivayam S, Gomez F, Fleegle JD; Tuberculosis Imaging Program; Arlehamn CSL, Sette A, Sher A, Freeman GJ, Via LE, Barry Iii CE, Barber DL.
Sakai S, et al. Among authors: dorosky de.
Mucosal Immunol. 2021 Sep;14(5):1055-1066. doi: 10.1038/s41385-021-00425-3. Epub 2021 Jun 22.
Mucosal Immunol. 2021.
PMID: 34158594
Free PMC article.
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CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection.
Foreman TW, Nelson CE, Kauffman KD, Lora NE, Vinhaes CL, Dorosky DE, Sakai S, Gomez F, Fleegle JD, Parham M, Perera SR, Lindestam Arlehamn CS, Sette A; Tuberculosis Imaging Program; Brenchley JM, Queiroz ATL, Andrade BB, Kabat J, Via LE, Barber DL.
Foreman TW, et al. Among authors: dorosky de.
Cell Rep. 2022 May 31;39(9):110896. doi: 10.1016/j.celrep.2022.110896.
Cell Rep. 2022.
PMID: 35649361
Free article.
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Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues.
Nelson CE, Namasivayam S, Foreman TW, Kauffman KD, Sakai S, Dorosky DE, Lora NE; NIAID/DIR Tuberculosis Imaging Program; Brooks K, Potter EL, Garza NL, Lafont BAP, Johnson RF, Roederer M, Sher A, Weiskopf D, Sette A, de Wit E, Hickman HD, Brenchley JM, Via LE, Barber DL.
Nelson CE, et al. Among authors: dorosky de.
Sci Immunol. 2022 Mar 10:eabo0535. doi: 10.1126/sciimmunol.abo0535. Online ahead of print.
Sci Immunol. 2022.
PMID: 35271298
Free PMC article.
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