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ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage.
Collins-Racie LA, Flannery CR, Zeng W, Corcoran C, Annis-Freeman B, Agostino MJ, Arai M, DiBlasio-Smith E, Dorner AJ, Georgiadis KE, Jin M, Tan XY, Morris EA, LaVallie ER. Collins-Racie LA, et al. Among authors: dorner aj. Matrix Biol. 2004 Jul;23(4):219-30. doi: 10.1016/j.matbio.2004.05.004. Matrix Biol. 2004. PMID: 15296936
Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system.
Arai M, Anderson D, Kurdi Y, Annis-Freeman B, Shields K, Collins-Racie LA, Corcoran C, DiBlasio-Smith E, Pittman DD, Dorner AJ, Morris E, LaVallie ER. Arai M, et al. Among authors: dorner aj. Osteoarthritis Cartilage. 2004 Aug;12(8):599-613. doi: 10.1016/j.joca.2004.05.001. Osteoarthritis Cartilage. 2004. PMID: 15262240 Free article.
Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.
LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M. LaVallie ER, et al. Among authors: dorner aj. J Biol Chem. 2006 Aug 25;281(34):24124-37. doi: 10.1074/jbc.M601905200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798739 Free article.
Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage: reduced LXR signaling contributes to catabolic metabolism typical of osteoarthritis.
Collins-Racie LA, Yang Z, Arai M, Li N, Majumdar MK, Nagpal S, Mounts WM, Dorner AJ, Morris E, LaVallie ER. Collins-Racie LA, et al. Among authors: dorner aj. Osteoarthritis Cartilage. 2009 Jul;17(7):832-42. doi: 10.1016/j.joca.2008.12.011. Epub 2009 Jan 19. Osteoarthritis Cartilage. 2009. PMID: 19217805 Free article.
Use of ex vivo systems for biomarker discovery.
Lavallie ER, Dorner AJ, Burczynski ME. Lavallie ER, et al. Among authors: dorner aj. Curr Opin Pharmacol. 2008 Oct;8(5):647-53. doi: 10.1016/j.coph.2008.08.003. Epub 2008 Sep 19. Curr Opin Pharmacol. 2008. PMID: 18771752 Review.
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
DiBlasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, Slager AM, Burczynski ME, Dorner AJ, LaVallie ER. DiBlasio-Smith EA, et al. Among authors: dorner aj. J Transl Med. 2008 Oct 16;6:59. doi: 10.1186/1479-5876-6-59. J Transl Med. 2008. PMID: 18925943 Free PMC article. Clinical Trial.
Measurement of myostatin concentrations in human serum: Circulating concentrations in young and older men and effects of testosterone administration.
Lakshman KM, Bhasin S, Corcoran C, Collins-Racie LA, Tchistiakova L, Forlow SB, St Ledger K, Burczynski ME, Dorner AJ, Lavallie ER. Lakshman KM, et al. Among authors: dorner aj. Mol Cell Endocrinol. 2009 Apr 10;302(1):26-32. doi: 10.1016/j.mce.2008.12.019. Epub 2009 Jan 21. Mol Cell Endocrinol. 2009. PMID: 19356623
In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2alpha overcomes the asthma-associated response.
Whalen KA, Legault H, Hang C, Hill A, Kasaian M, Donaldson D, Bensch GW, Bensch G, Baker J, Reddy PS, Wood N, Ramarao MK, Ellis DK, Csimma C, McKee C, Clark JD, Ryan J, Dorner AJ, O'Toole M. Whalen KA, et al. Among authors: dorner aj. Clin Exp Allergy. 2008 Oct;38(10):1590-605. doi: 10.1111/j.1365-2222.2008.03059.x. Epub 2008 Jul 28. Clin Exp Allergy. 2008. PMID: 18665843 Free PMC article.
89 results