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PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association.
Proske M, Janowski R, Bacher S, Kang HS, Monecke T, Koehler T, Hutten S, Tretter J, Crois A, Molitor L, Varela-Rial A, Fino R, Donati E, De Fabritiis G, Dormann D, Sattler M, Niessing D. Proske M, et al. Among authors: dormann d. Elife. 2024 Apr 24;13:RP93561. doi: 10.7554/eLife.93561. Elife. 2024. PMID: 38655849 Free PMC article.
The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.
Zibold J, Lessard LER, Picard F, da Silva LG, Zadorozhna Y, Streichenberger N, Belotti E, Osseni A, Emerit A, Errazuriz-Cerda E, Michel-Calemard L, Menassa R, Coudert L, Wiessner M, Stucka R, Klopstock T, Simonetti F, Hutten S, Nonaka T, Hasegawa M, Strom TM, Bernard E, Ollagnon E, Urtizberea A, Dormann D, Petiot P, Schaeffer L, Senderek J, Leblanc P. Zibold J, et al. Among authors: dormann d. Brain. 2024 May 3;147(5):1768-1783. doi: 10.1093/brain/awad410. Brain. 2024. PMID: 38079474 Free PMC article.
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Riemenschneider H, Simonetti F, Sheth U, Katona E, Roth S, Hutten S, Farny D, Michaelsen M, Nuscher B, Schmidt MK, Flatley A, Schepers A, Gruijs da Silva LA, Zhou Q, Klopstock T, Liesz A, Arzberger T, Herms J, Feederle R, Gendron TF, Dormann D, Edbauer D. Riemenschneider H, et al. Among authors: dormann d. Acta Neuropathol Commun. 2023 Jul 11;11(1):112. doi: 10.1186/s40478-023-01592-z. Acta Neuropathol Commun. 2023. PMID: 37434215 Free PMC article.
Creating overview and summary figures.
Critcher M, Gruijs da Silva LA, Dormann D, Campbell ZT, Le TK, Rocchi P, Sorgenfrei M. Critcher M, et al. Among authors: dormann d. Trends Biochem Sci. 2023 Feb;48(2):97-99. doi: 10.1016/j.tibs.2022.09.009. Trends Biochem Sci. 2023. PMID: 36669467 No abstract available.
TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.
Zambusi A, Novoselc KT, Hutten S, Kalpazidou S, Koupourtidou C, Schieweck R, Aschenbroich S, Silva L, Yazgili AS, van Bebber F, Schmid B, Möller G, Tritscher C, Stigloher C, Delbridge C, Sirko S, Günes ZI, Liebscher S, Schlegel J, Aliee H, Theis F, Meiners S, Kiebler M, Dormann D, Ninkovic J. Zambusi A, et al. Among authors: dormann d. Nat Neurosci. 2022 Dec;25(12):1608-1625. doi: 10.1038/s41593-022-01199-y. Epub 2022 Nov 24. Nat Neurosci. 2022. PMID: 36424432
Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters.
Robles-Rebollo I, Cuartero S, Canellas-Socias A, Wells S, Karimi MM, Mereu E, Chivu AG, Heyn H, Whilding C, Dormann D, Marguerat S, Rioja I, Prinjha RK, Stumpf MPH, Fisher AG, Merkenschlager M. Robles-Rebollo I, et al. Among authors: dormann d. Nat Commun. 2022 Jul 27;13(1):4342. doi: 10.1038/s41467-022-31192-9. Nat Commun. 2022. PMID: 35896525 Free PMC article.
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.
Strohm L, Hu Z, Suk Y, Rühmkorf A, Sternburg E, Gattringer V, Riemenschneider H, Berutti R, Graf E, Weishaupt JH, Brill MS, Harbauer AB, Dormann D, Dengjel J, Edbauer D, Behrends C. Strohm L, et al. Among authors: dormann d. Life Sci Alliance. 2022 Jul 1;5(11):e202101327. doi: 10.26508/lsa.202101327. Print 2022 Nov. Life Sci Alliance. 2022. PMID: 35777956 Free PMC article.
PragmaTic, prospEctive, randomized, controlled, double-blind, mulTi-centre, multinational study on the safety and efficacy of a 6% HydroxYethyl Starch (HES) solution versus an electrolyte solution in trauma patients: study protocol for the TETHYS study.
Palma CD, Mamba M, Geldenhuys J, Fadahun O, Rossaint R, Zacharowski K, Brand M, Díaz-Cambronero Ó, Belda J, Westphal M, Brauer U, Dormann D, Dehnhardt T, Hernandez-Gonzalez M, Schmier S, de Korte D, Plani F, Buhre W. Palma CD, et al. Among authors: dormann d. Trials. 2022 Jun 2;23(1):456. doi: 10.1186/s13063-022-06390-x. Trials. 2022. PMID: 35655234 Free PMC article.
Only solid waste, please!
Dormann D, Behrends C. Dormann D, et al. Mol Cell. 2022 Apr 21;82(8):1408-1410. doi: 10.1016/j.molcel.2022.04.003. Mol Cell. 2022. PMID: 35452612 Free article.
93 results