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Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.
J Med Chem. 2011 May 12;54(9):3241-50. doi: 10.1021/jm200135z. Epub 2011 Apr 15.
J Med Chem. 2011.
PMID: 21456623
Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy.
De Moor O, Dorgan CR, Johnson PD, Lambert AG, Lecci C, Maillol C, Nugent G, Poignant SD, Price PD, Pye RJ, Storer R, Tinsley JM, Vickers R, Well Rv, Wilkes FJ, Wilson FX, Wren SP, Wynne GM.
De Moor O, et al. Among authors: dorgan cr.
Bioorg Med Chem Lett. 2011 Aug 15;21(16):4828-31. doi: 10.1016/j.bmcl.2011.06.047. Epub 2011 Jun 17.
Bioorg Med Chem Lett. 2011.
PMID: 21741236
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The discovery of a novel antibiotic for the treatment of Clostridium difficile infections: a story of an effective academic-industrial partnership.
Mann J, Taylor PW, Dorgan CR, Johnson PD, Wilson FX, Vickers R, Dale AG, Neidle S.
Mann J, et al. Among authors: dorgan cr.
Medchemcomm. 2015 Aug 5;6(8):1420-1426. doi: 10.1039/c5md00238a. Epub 2015 Jul 20.
Medchemcomm. 2015.
PMID: 26949507
Free PMC article.
Review.
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RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines.
Nievergelt P, Berliat F, McAuley KE, Dorgan CR, van Well RM, Thorn A, Spingler B.
Nievergelt P, et al. Among authors: dorgan cr.
ChemMedChem. 2024 Apr 2;19(7):e202300600. doi: 10.1002/cmdc.202300600. Epub 2024 Feb 29.
ChemMedChem. 2024.
PMID: 38235959
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A new method testing the orthogonality of different protecting groups.
Ágoston K, Ágoston Á, Dorgan CR, Fügedi P.
Ágoston K, et al. Among authors: dorgan cr.
Carbohydr Res. 2015 Dec 11;418:98-103. doi: 10.1016/j.carres.2015.10.007. Epub 2015 Oct 23.
Carbohydr Res. 2015.
PMID: 26580711
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