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A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.
Sison-Young RL, Lauschke VM, Johann E, Alexandre E, Antherieu S, Aerts H, Gerets HHJ, Labbe G, Hoët D, Dorau M, Schofield CA, Lovatt CA, Holder JC, Stahl SH, Richert L, Kitteringham NR, Jones RP, Elmasry M, Weaver RJ, Hewitt PG, Ingelman-Sundberg M, Goldring CE, Park BK. Sison-Young RL, et al. Among authors: dorau m. Arch Toxicol. 2017 Mar;91(3):1385-1400. doi: 10.1007/s00204-016-1745-4. Epub 2016 Jun 25. Arch Toxicol. 2017. PMID: 27344343 Free PMC article.
Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites.
Ackerson T, Amberg A, Atzrodt J, Arabeyre C, Defossa E, Dorau M, Dudda A, Dwyer J, Holla W, Kissner T, Kohlmann M, Kürzel U, Pánczél J, Rajanna S, Riedel J, Schmidt F, Wäse K, Weitz D, Derdau V. Ackerson T, et al. Among authors: dorau m. J Biochem Mol Toxicol. 2019 Aug;33(8):e22345. doi: 10.1002/jbt.22345. Epub 2019 May 8. J Biochem Mol Toxicol. 2019. PMID: 31066974
A multi-institutional study benchmarking the zebrafish developmental assay for prediction of embryotoxic plasma concentrations from rat embryo-fetal development studies.
Cassar S, Beekhuijzen M, Beyer B, Chapin R, Dorau M, Hoberman A, Krupp E, Leconte I, Stedman D, Stethem C, van den Oetelaar D, Tornesi B. Cassar S, et al. Among authors: dorau m. Reprod Toxicol. 2019 Jun;86:33-44. doi: 10.1016/j.reprotox.2019.02.004. Epub 2019 Mar 13. Reprod Toxicol. 2019. PMID: 30876927 Free article.
Chain-End Effects on Supramolecular Poly(ethylene glycol) Polymers.
Brás A, Arizaga A, Agirre U, Dorau M, Houston J, Radulescu A, Kruteva M, Pyckhout-Hintzen W, Schmidt AM. Brás A, et al. Among authors: dorau m. Polymers (Basel). 2021 Jul 7;13(14):2235. doi: 10.3390/polym13142235. Polymers (Basel). 2021. PMID: 34300992 Free PMC article.
[Hepatitis C (personal observations].
Halota W, Lapniewska E, Trzciński J, Opoka J, Topczewska E, Dorau M. Halota W, et al. Among authors: dorau m. Przegl Epidemiol. 1991;45(4):297-9. Przegl Epidemiol. 1991. PMID: 1841405 Polish.