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Page 1
HCV E2 core structures and mAbs: something is still missing.
Castelli M, Clementi N, Sautto GA, Pfaff J, Kahle KM, Barnes T, Doranz BJ, Dal Peraro M, Clementi M, Burioni R, Mancini N. Castelli M, et al. Among authors: doranz bj. Drug Discov Today. 2014 Dec;19(12):1964-70. doi: 10.1016/j.drudis.2014.08.011. Epub 2014 Aug 27. Drug Discov Today. 2014. PMID: 25172800 Free PMC article. Review.
Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity.
Jensen JL, Sankhala RS, Dussupt V, Bai H, Hajduczki A, Lal KG, Chang WC, Martinez EJ, Peterson CE, Golub ES, Rees PA, Mendez-Rivera L, Zemil M, Kavusak E, Mayer SV, Wieczorek L, Kannan S, Doranz BJ, Davidson E, Yang ES, Zhang Y, Chen M, Choe M, Wang L, Gromowski GD, Koup RA, Michael NL, Polonis VR, Rolland M, Modjarrad K, Krebs SJ, Joyce MG. Jensen JL, et al. Among authors: doranz bj. J Virol. 2023 Jul 27;97(7):e0159622. doi: 10.1128/jvi.01596-22. Epub 2023 Jul 3. J Virol. 2023. PMID: 37395646 Free PMC article.
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.
Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Duran V, Rebellon-Sanchez DE, Sanz AM, Rosso F, Doranz BJ, Einav S, Matsen Iv FA, Goo L. Lubow J, et al. Among authors: doranz bj. PLoS Pathog. 2023 Oct 9;19(10):e1011722. doi: 10.1371/journal.ppat.1011722. eCollection 2023 Oct. PLoS Pathog. 2023. PMID: 37812640 Free PMC article.
Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop.
Costin JM, Zaitseva E, Kahle KM, Nicholson CO, Rowe DK, Graham AS, Bazzone LE, Hogancamp G, Figueroa Sierra M, Fong RH, Yang ST, Lin L, Robinson JE, Doranz BJ, Chernomordik LV, Michael SF, Schieffelin JS, Isern S. Costin JM, et al. Among authors: doranz bj. J Virol. 2013 Jan;87(1):52-66. doi: 10.1128/JVI.02273-12. Epub 2012 Oct 17. J Virol. 2013. PMID: 23077306 Free PMC article.
A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease.
Selvarajah S, Sexton NR, Kahle KM, Fong RH, Mattia KA, Gardner J, Lu K, Liss NM, Salvador B, Tucker DF, Barnes T, Mabila M, Zhou X, Rossini G, Rucker JB, Sanders DA, Suhrbier A, Sambri V, Michault A, Muench MO, Doranz BJ, Simmons G. Selvarajah S, et al. Among authors: doranz bj. PLoS Negl Trop Dis. 2013 Sep 12;7(9):e2423. doi: 10.1371/journal.pntd.0002423. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24069479 Free PMC article.
Atomic-level functional model of dengue virus Envelope protein infectivity.
Christian EA, Kahle KM, Mattia K, Puffer BA, Pfaff JM, Miller A, Paes C, Davidson E, Doranz BJ. Christian EA, et al. Among authors: doranz bj. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18662-7. doi: 10.1073/pnas.1310962110. Epub 2013 Oct 24. Proc Natl Acad Sci U S A. 2013. PMID: 24158478 Free PMC article.
The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein.
Smith SA, de Alwis AR, Kose N, Harris E, Ibarra KD, Kahle KM, Pfaff JM, Xiang X, Doranz BJ, de Silva AM, Austin SK, Sukupolvi-Petty S, Diamond MS, Crowe JE Jr. Smith SA, et al. Among authors: doranz bj. mBio. 2013 Nov 19;4(6):e00873-13. doi: 10.1128/mBio.00873-13. mBio. 2013. PMID: 24255124 Free PMC article.
Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity.
Messer WB, de Alwis R, Yount BL, Royal SR, Huynh JP, Smith SA, Crowe JE Jr, Doranz BJ, Kahle KM, Pfaff JM, White LJ, Sariol CA, de Silva AM, Baric RS. Messer WB, et al. Among authors: doranz bj. Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1939-44. doi: 10.1073/pnas.1317350111. Epub 2014 Jan 2. Proc Natl Acad Sci U S A. 2014. PMID: 24385585 Free PMC article. Retracted.
Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy.
Fong RH, Banik SS, Mattia K, Barnes T, Tucker D, Liss N, Lu K, Selvarajah S, Srinivasan S, Mabila M, Miller A, Muench MO, Michault A, Rucker JB, Paes C, Simmons G, Kahle KM, Doranz BJ. Fong RH, et al. Among authors: doranz bj. J Virol. 2014 Dec;88(24):14364-79. doi: 10.1128/JVI.01943-14. Epub 2014 Oct 1. J Virol. 2014. PMID: 25275138 Free PMC article.
123 results