Dooley S - Search Results

1

BMP-9 interferes with liver regeneration and promotes liver fibrosis.

Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P. Breitkopf-Heinlein K, et al. Among authors: dooley s. Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23. Gut. 2017. PMID: 28336518

2

Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats.

Dooley S, Hamzavi J, Breitkopf K, Wiercinska E, Said HM, Lorenzen J, Ten Dijke P, Gressner AM. Dooley S, et al. Gastroenterology. 2003 Jul;125(1):178-91. doi: 10.1016/s0016-5085(03)00666-8. Gastroenterology. 2003. PMID: 12851882

3

Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells.

Breitkopf K, Sawitza I, Westhoff JH, Wickert L, Dooley S, Gressner AM. Breitkopf K, et al. Among authors: dooley s. Gut. 2005 May;54(5):673-81. doi: 10.1136/gut.2004.042911. Gut. 2005. PMID: 15831915 Free PMC article.

4

Transdifferentiation-dependent expression of alpha-SMA in hepatic stellate cells does not involve TGF-beta pathways leading to coinduction of collagen type I and thrombospondin-2.

Lindert S, Wickert L, Sawitza I, Wiercinska E, Gressner AM, Dooley S, Breitkopf K. Lindert S, et al. Among authors: dooley s. Matrix Biol. 2005 May;24(3):198-207. doi: 10.1016/j.matbio.2005.03.003. Matrix Biol. 2005. PMID: 15905080

5

Anti-TGF-beta strategies for the treatment of chronic liver disease.

Breitkopf K, Haas S, Wiercinska E, Singer MV, Dooley S. Breitkopf K, et al. Among authors: dooley s. Alcohol Clin Exp Res. 2005 Nov;29(11 Suppl):121S-131S. doi: 10.1097/01.alc.0000189284.98684.22. Alcohol Clin Exp Res. 2005. PMID: 16344596 Review.

6

Id1 is a critical mediator in TGF-beta-induced transdifferentiation of rat hepatic stellate cells.

Wiercinska E, Wickert L, Denecke B, Said HM, Hamzavi J, Gressner AM, Thorikay M, ten Dijke P, Mertens PR, Breitkopf K, Dooley S. Wiercinska E, et al. Among authors: dooley s. Hepatology. 2006 May;43(5):1032-41. doi: 10.1002/hep.21135. Hepatology. 2006. PMID: 16628634

7

Liver fibrogenesis due to cholestasis is associated with increased Smad7 expression and Smad3 signaling.

Seyhan H, Hamzavi J, Wiercinska E, Gressner AM, Mertens PR, Kopp J, Horch RE, Breitkopf K, Dooley S. Seyhan H, et al. Among authors: dooley s. J Cell Mol Med. 2006 Oct-Dec;10(4):922-32. doi: 10.1111/j.1582-4934.2006.tb00535.x. J Cell Mol Med. 2006. PMID: 17125595 Free PMC article.

8

Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.

Klingmüller U, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Götschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preiss R, MacNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weizsäcker F, Hengstler JG. Klingmüller U, et al. Among authors: dooley s. Syst Biol (Stevenage). 2006 Nov;153(6):433-47. doi: 10.1049/ip-syb:20050067. Syst Biol (Stevenage). 2006. PMID: 17186705

9

Transforming growth factor beta1 up-regulates interferon regulatory factor 8 during dendritic cell development.

Ju XS, Ruau D, Jäntti P, Seré K, Becker C, Wiercinska E, Bartz C, Erdmann B, Dooley S, Zenke M. Ju XS, et al. Among authors: dooley s. Eur J Immunol. 2007 May;37(5):1174-83. doi: 10.1002/eji.200636504. Eur J Immunol. 2007. PMID: 17429842 Free article.

10

Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.

Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S. Weng HL, et al. Among authors: dooley s. Hepatology. 2007 Oct;46(4):1257-70. doi: 10.1002/hep.21806. Hepatology. 2007. PMID: 17657819

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