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Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.
Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG. Godoy P, et al. Among authors: dooley s. Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23. Arch Toxicol. 2016. PMID: 27339419 Free PMC article.
TGF-beta/Smad signaling in the injured liver.
Breitkopf K, Godoy P, Ciuclan L, Singer MV, Dooley S. Breitkopf K, et al. Among authors: dooley s. Z Gastroenterol. 2006 Jan;44(1):57-66. doi: 10.1055/s-2005-858989. Z Gastroenterol. 2006. PMID: 16397841 Review.
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.
Klingmüller U, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Götschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preiss R, MacNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weizsäcker F, Hengstler JG. Klingmüller U, et al. Among authors: dooley s. Syst Biol (Stevenage). 2006 Nov;153(6):433-47. doi: 10.1049/ip-syb:20050067. Syst Biol (Stevenage). 2006. PMID: 17186705
TGF-beta signaling in alcohol induced hepatic injury.
Meyer C, Meindl-Beinker NM, Dooley S. Meyer C, et al. Among authors: dooley s. Front Biosci (Landmark Ed). 2010 Jan 1;15(2):740-9. doi: 10.2741/3643. Front Biosci (Landmark Ed). 2010. PMID: 20036843 Free article. Review.
460 results