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Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activity.
Menna E, Zambetti S, Morini R, Donzelli A, Disanza A, Calvigioni D, Braida D, Nicolini C, Orlando M, Fossati G, Cristina Regondi M, Pattini L, Frassoni C, Francolini M, Scita G, Sala M, Fahnestock M, Matteoli M. Menna E, et al. Among authors: donzelli a. EMBO J. 2013 Jun 12;32(12):1730-44. doi: 10.1038/emboj.2013.107. Epub 2013 May 17. EMBO J. 2013. PMID: 23685357 Free PMC article.
Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a neurobehavioral model of autism.
Sala M, Braida D, Lentini D, Busnelli M, Bulgheroni E, Capurro V, Finardi A, Donzelli A, Pattini L, Rubino T, Parolaro D, Nishimori K, Parenti M, Chini B. Sala M, et al. Among authors: donzelli a. Biol Psychiatry. 2011 May 1;69(9):875-82. doi: 10.1016/j.biopsych.2010.12.022. Epub 2011 Feb 21. Biol Psychiatry. 2011. PMID: 21306704
Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.
Corradini I, Donzelli A, Antonucci F, Welzl H, Loos M, Martucci R, De Astis S, Pattini L, Inverardi F, Wolfer D, Caleo M, Bozzi Y, Verderio C, Frassoni C, Braida D, Clerici M, Lipp HP, Sala M, Matteoli M. Corradini I, et al. Among authors: donzelli a. Cereb Cortex. 2014 Feb;24(2):364-76. doi: 10.1093/cercor/bhs316. Epub 2012 Oct 12. Cereb Cortex. 2014. PMID: 23064108 Free article.
Mice heterozygous for the oxytocin receptor gene (Oxtr(+/-)) show impaired social behaviour but not increased aggression or cognitive inflexibility: evidence of a selective haploinsufficiency gene effect.
Sala M, Braida D, Donzelli A, Martucci R, Busnelli M, Bulgheroni E, Rubino T, Parolaro D, Nishimori K, Chini B. Sala M, et al. Among authors: donzelli a. J Neuroendocrinol. 2013 Feb;25(2):107-18. doi: 10.1111/j.1365-2826.2012.02385.x. J Neuroendocrinol. 2013. PMID: 22967062
78 results