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A bacteriophage endolysin that eliminates intracellular streptococci.
Shen Y, Barros M, Vennemann T, Gallagher DT, Yin Y, Linden SB, Heselpoth RD, Spencer DJ, Donovan DM, Moult J, Fischetti VA, Heinrich F, Lösche M, Nelson DC. Shen Y, et al. Among authors: donovan dm. Elife. 2016 Mar 15;5:e13152. doi: 10.7554/eLife.13152. Elife. 2016. PMID: 26978792 Free PMC article.
Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection.
Schmelcher M, Shen Y, Nelson DC, Eugster MR, Eichenseher F, Hanke DC, Loessner MJ, Dong S, Pritchard DG, Lee JC, Becker SC, Foster-Frey J, Donovan DM. Schmelcher M, et al. Among authors: donovan dm. J Antimicrob Chemother. 2015 May;70(5):1453-65. doi: 10.1093/jac/dku552. Epub 2015 Jan 27. J Antimicrob Chemother. 2015. PMID: 25630640 Free PMC article.
Endolysins as antimicrobials.
Nelson DC, Schmelcher M, Rodriguez-Rubio L, Klumpp J, Pritchard DG, Dong S, Donovan DM. Nelson DC, et al. Among authors: donovan dm. Adv Virus Res. 2012;83:299-365. doi: 10.1016/B978-0-12-394438-2.00007-4. Adv Virus Res. 2012. PMID: 22748813 Review.
Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus.
Becker SC, Roach DR, Chauhan VS, Shen Y, Foster-Frey J, Powell AM, Bauchan G, Lease RA, Mohammadi H, Harty WJ, Simmons C, Schmelcher M, Camp M, Dong S, Baker JR, Sheen TR, Doran KS, Pritchard DG, Almeida RA, Nelson DC, Marriott I, Lee JC, Donovan DM. Becker SC, et al. Among authors: donovan dm. Sci Rep. 2016 Apr 28;6:25063. doi: 10.1038/srep25063. Sci Rep. 2016. PMID: 27121552 Free PMC article.
Characterization of LysBC17, a Lytic Endopeptidase from Bacillus cereus.
Swift SM, Etobayeva IV, Reid KP, Waters JJ, Oakley BB, Donovan DM, Nelson DC. Swift SM, et al. Among authors: donovan dm. Antibiotics (Basel). 2019 Sep 19;8(3):155. doi: 10.3390/antibiotics8030155. Antibiotics (Basel). 2019. PMID: 31546935 Free PMC article.
293 results