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The Streptococcus agalactiae complement interfering protein combines multiple complement-inhibitory mechanisms by interacting with both C4 and C3 ligands.
Giussani S, Pietrocola G, Donnarumma D, Norais N, Speziale P, Fabbrini M, Margarit I. Giussani S, et al. Among authors: donnarumma d. FASEB J. 2019 Mar;33(3):4448-4457. doi: 10.1096/fj.201801991R. Epub 2018 Dec 19. FASEB J. 2019. PMID: 30566365 Free PMC article.
The data obtained reveal a new role for this GBS polypeptide at the interface between the innate and adaptive immune responses, adding a new member to the growing list of virulence factors secreted by gram-positive pathogens that incorporate multiple immunomodulatory functions.-G …
The data obtained reveal a new role for this GBS polypeptide at the interface between the innate and adaptive immune responses, adding a new …
Neisseria meningitis GNA1030 is a ubiquinone-8 binding protein.
Donnarumma D, Golfieri G, Brier S, Castagnini M, Veggi D, Bottomley MJ, Delany I, Norais N. Donnarumma D, et al. FASEB J. 2015 Jun;29(6):2260-7. doi: 10.1096/fj.14-263954. Epub 2015 Feb 20. FASEB J. 2015. PMID: 25713028
Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies.
Ciferri C, Chandramouli S, Leitner A, Donnarumma D, Cianfrocco MA, Gerrein R, Friedrich K, Aggarwal Y, Palladino G, Aebersold R, Norais N, Settembre EC, Carfi A. Ciferri C, et al. Among authors: donnarumma d. PLoS Pathog. 2015 Oct 20;11(10):e1005230. doi: 10.1371/journal.ppat.1005230. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26485028 Free PMC article.
Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections.
Nuccitelli A, Cozzi R, Gourlay LJ, Donnarumma D, Necchi F, Norais N, Telford JL, Rappuoli R, Bolognesi M, Maione D, Grandi G, Rinaudo CD. Nuccitelli A, et al. Among authors: donnarumma d. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10278-83. doi: 10.1073/pnas.1106590108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593422 Free PMC article.
Native State Organization of Outer Membrane Porins Unraveled by HDx-MS.
Donnarumma D, Maestri C, Giammarinaro PI, Capriotti L, Bartolini E, Veggi D, Petracca R, Scarselli M, Norais N. Donnarumma D, et al. J Proteome Res. 2018 May 4;17(5):1794-1800. doi: 10.1021/acs.jproteome.7b00830. Epub 2018 Apr 17. J Proteome Res. 2018. PMID: 29619829 Free article.
Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries.
Domina M, Lanza Cariccio V, Benfatto S, Venza M, Venza I, Donnarumma D, Bartolini E, Borgogni E, Bruttini M, Santini L, Midiri A, Galbo R, Romeo L, Patanè F, Biondo C, Norais N, Masignani V, Teti G, Felici F, Beninati C. Domina M, et al. Among authors: donnarumma d. PLoS One. 2016 Aug 10;11(8):e0160702. doi: 10.1371/journal.pone.0160702. eCollection 2016. PLoS One. 2016. PMID: 27508302 Free PMC article.
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