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Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment.
Nicolas-Boluda A, Vaquero J, Vimeux L, Guilbert T, Barrin S, Kantari-Mimoun C, Ponzo M, Renault G, Deptula P, Pogoda K, Bucki R, Cascone I, Courty J, Fouassier L, Gazeau F, Donnadieu E. Nicolas-Boluda A, et al. Among authors: donnadieu e. Elife. 2021 Jun 9;10:e58688. doi: 10.7554/eLife.58688. Elife. 2021. PMID: 34106045 Free PMC article.
Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment.
Peranzoni E, Lemoine J, Vimeux L, Feuillet V, Barrin S, Kantari-Mimoun C, Bercovici N, Guérin M, Biton J, Ouakrim H, Régnier F, Lupo A, Alifano M, Damotte D, Donnadieu E. Peranzoni E, et al. Among authors: donnadieu e. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4041-E4050. doi: 10.1073/pnas.1720948115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632196 Free PMC article.
Obstacles to T cell migration in the tumor microenvironment.
Nicolas-Boluda A, Donnadieu E. Nicolas-Boluda A, et al. Among authors: donnadieu e. Comp Immunol Microbiol Infect Dis. 2019 Apr;63:22-30. doi: 10.1016/j.cimid.2018.12.006. Epub 2018 Dec 27. Comp Immunol Microbiol Infect Dis. 2019. PMID: 30961814
TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors.
Guerin MV, Regnier F, Feuillet V, Vimeux L, Weiss JM, Bismuth G, Altan-Bonnet G, Guilbert T, Thoreau M, Finisguerra V, Donnadieu E, Trautmann A, Bercovici N. Guerin MV, et al. Among authors: donnadieu e. Nat Commun. 2019 Sep 11;10(1):4131. doi: 10.1038/s41467-019-11998-w. Nat Commun. 2019. PMID: 31511510 Free PMC article.
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha BL, Dantes Z, Rataj F, Dorman K, Lutz J, Karches CH, Heise C, Kurzay M, Larimer BM, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth C, Benmebarek MR, Dhoqina D, Grünmeier R, Seifert M, Oener A, Umut Ö, Joaquina S, Vimeux L, Tran T, Hank T, Baba T, Huynh D, Megens RTA, Janssen KP, Jastroch M, Lamp D, Ruehland S, Di Pilato M, Pruessmann JN, Thomas M, Marr C, Ormanns S, Reischer A, Hristov M, Tartour E, Donnadieu E, Rothenfusser S, Duewell P, König LM, Schnurr M, Subklewe M, Liss AS, Halama N, Reichert M, Mempel TR, Endres S, Kobold S. Lesch S, et al. Among authors: donnadieu e. Nat Biomed Eng. 2021 Nov;5(11):1246-1260. doi: 10.1038/s41551-021-00737-6. Epub 2021 Jun 3. Nat Biomed Eng. 2021. PMID: 34083764 Free PMC article.
83 results