Dong M - Search Results

1

Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants.

Tian S, Xiong X, Zeng J, Wang S, Tremblay BJ, Chen P, Chen B, Liu M, Chen P, Sheng K, Zeve D, Qi W, Breault DT, Rodríguez C, Gerhard R, Jin R, Doxey AC, Dong M. Tian S, et al. Among authors: dong m. Nat Commun. 2022 Nov 9;13(1):6786. doi: 10.1038/s41467-022-33964-9. Nat Commun. 2022. PMID: 36351897 Free PMC article.

2

Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex.

Lee K, Zhong X, Gu S, Kruel AM, Dorner MB, Perry K, Rummel A, Dong M, Jin R. Lee K, et al. Among authors: dong m. Science. 2014 Jun 20;344(6190):1405-10. doi: 10.1126/science.1253823. Science. 2014. PMID: 24948737 Free PMC article.

3

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.

Yao G, Zhang S, Mahrhold S, Lam KH, Stern D, Bagramyan K, Perry K, Kalkum M, Rummel A, Dong M, Jin R. Yao G, et al. Among authors: dong m. Nat Struct Mol Biol. 2016 Jul;23(7):656-62. doi: 10.1038/nsmb.3245. Epub 2016 Jun 13. Nat Struct Mol Biol. 2016. PMID: 27294781 Free PMC article.

4

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.

Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, Zhang X, Stallcup WB, Miao J, He X, Hurdle JG, Breault DT, Brass AL, Dong M. Tao L, et al. Among authors: dong m. Nature. 2016 Oct 20;538(7625):350-355. doi: 10.1038/nature19799. Epub 2016 Sep 28. Nature. 2016. PMID: 27680706 Free PMC article.

5

Identification and characterization of a novel botulinum neurotoxin.

Zhang S, Masuyer G, Zhang J, Shen Y, Lundin D, Henriksson L, Miyashita SI, Martínez-Carranza M, Dong M, Stenmark P. Zhang S, et al. Among authors: dong m. Nat Commun. 2017 Aug 3;8:14130. doi: 10.1038/ncomms14130. Nat Commun. 2017. PMID: 28770820 Free PMC article.

6

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.

Yao G, Lam KH, Weisemann J, Peng L, Krez N, Perry K, Shoemaker CB, Dong M, Rummel A, Jin R. Yao G, et al. Among authors: dong m. Sci Rep. 2017 Aug 7;7(1):7438. doi: 10.1038/s41598-017-07457-5. Sci Rep. 2017. PMID: 28785006 Free PMC article.

7

Massively parallel de novo protein design for targeted therapeutics.

Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, Jenkins CM, Colvin T, Carter L, Bohn A, Bryan CM, Fernández-Velasco DA, Stewart L, Dong M, Huang X, Jin R, Wilson IA, Fuller DH, Baker D. Chevalier A, et al. Among authors: dong m. Nature. 2017 Oct 5;550(7674):74-79. doi: 10.1038/nature23912. Epub 2017 Sep 27. Nature. 2017. PMID: 28953867 Free PMC article.

8

Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.

Zhang S, Berntsson RP, Tepp WH, Tao L, Johnson EA, Stenmark P, Dong M. Zhang S, et al. Among authors: dong m. Nat Commun. 2017 Nov 21;8(1):1637. doi: 10.1038/s41467-017-01534-z. Nat Commun. 2017. PMID: 29158482 Free PMC article.

9

Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.

Zhang S, Lebreton F, Mansfield MJ, Miyashita SI, Zhang J, Schwartzman JA, Tao L, Masuyer G, Martínez-Carranza M, Stenmark P, Gilmore MS, Doxey AC, Dong M. Zhang S, et al. Among authors: dong m. Cell Host Microbe. 2018 Feb 14;23(2):169-176.e6. doi: 10.1016/j.chom.2017.12.018. Epub 2018 Jan 27. Cell Host Microbe. 2018. PMID: 29396040 Free PMC article.

10

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B.

Chen P, Tao L, Wang T, Zhang J, He A, Lam KH, Liu Z, He X, Perry K, Dong M, Jin R. Chen P, et al. Among authors: dong m. Science. 2018 May 11;360(6389):664-669. doi: 10.1126/science.aar1999. Science. 2018. PMID: 29748286 Free PMC article.

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