Dong M - Search Results

1

Clostridioides difficile spore: coat assembly and formation.

Zeng J, Wang H, Dong M, Tian GB. Zeng J, et al. Among authors: dong m. Emerg Microbes Infect. 2022 Dec;11(1):2340-2349. doi: 10.1080/22221751.2022.2119168. Emerg Microbes Infect. 2022. PMID: 36032037 Free PMC article. Review.

2

Genome-Wide CRISPR Screen Identifies Semaphorin 6A and 6B as Receptors for Paeniclostridium sordellii Toxin TcsL.

Tian S, Liu Y, Wu H, Liu H, Zeng J, Choi MY, Chen H, Gerhard R, Dong M. Tian S, et al. Among authors: dong m. Cell Host Microbe. 2020 May 13;27(5):782-792.e7. doi: 10.1016/j.chom.2020.03.007. Epub 2020 Apr 16. Cell Host Microbe. 2020. PMID: 32302524 Free PMC article.

3

Receptor Binding Domains of TcdB from Clostridioides difficile for Chondroitin Sulfate Proteoglycan-4 and Frizzled Proteins Are Functionally Independent and Additive.

Henkel D, Tatge H, Schöttelndreier D, Tao L, Dong M, Gerhard R. Henkel D, et al. Among authors: dong m. Toxins (Basel). 2020 Nov 24;12(12):736. doi: 10.3390/toxins12120736. Toxins (Basel). 2020. PMID: 33255261 Free PMC article.

4

Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B.

Mansfield MJ, Tremblay BJ, Zeng J, Wei X, Hodgins H, Worley J, Bry L, Dong M, Doxey AC. Mansfield MJ, et al. Among authors: dong m. PLoS Pathog. 2020 Dec 28;16(12):e1009181. doi: 10.1371/journal.ppat.1009181. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33370413 Free PMC article.

5

Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.

Chen P, Zeng J, Liu Z, Thaker H, Wang S, Tian S, Zhang J, Tao L, Gutierrez CB, Xing L, Gerhard R, Huang L, Dong M, Jin R. Chen P, et al. Among authors: dong m. Nat Commun. 2021 Jun 18;12(1):3748. doi: 10.1038/s41467-021-23878-3. Nat Commun. 2021. PMID: 34145250 Free PMC article.

6

Ebselen Not Only Inhibits Clostridioides difficile Toxins but Displays Redox-Associated Cellular Killing.

Marreddy RKR, Olaitan AO, May JN, Dong M, Hurdle JG. Marreddy RKR, et al. Among authors: dong m. Microbiol Spectr. 2021 Oct 31;9(2):e0044821. doi: 10.1128/Spectrum.00448-21. Epub 2021 Sep 1. Microbiol Spectr. 2021. PMID: 34468187 Free PMC article.

7

Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.

Liu Z, Zhang S, Chen P, Tian S, Zeng J, Perry K, Dong M, Jin R. Liu Z, et al. Among authors: dong m. Sci Adv. 2021 Oct 22;7(43):eabi4582. doi: 10.1126/sciadv.abi4582. Epub 2021 Oct 22. Sci Adv. 2021. PMID: 34678063 Free PMC article.

8

Structure and conformational dynamics of Clostridioides difficile toxin A.

Chen B, Basak S, Chen P, Zhang C, Perry K, Tian S, Yu C, Dong M, Huang L, Bowen ME, Jin R. Chen B, et al. Among authors: dong m. Life Sci Alliance. 2022 Mar 15;5(6):e202201383. doi: 10.26508/lsa.202201383. Print 2022 Jun. Life Sci Alliance. 2022. PMID: 35292538 Free PMC article.

9

Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants.

Tian S, Xiong X, Zeng J, Wang S, Tremblay BJ, Chen P, Chen B, Liu M, Chen P, Sheng K, Zeve D, Qi W, Breault DT, Rodríguez C, Gerhard R, Jin R, Doxey AC, Dong M. Tian S, et al. Among authors: dong m. Nat Commun. 2022 Nov 9;13(1):6786. doi: 10.1038/s41467-022-33964-9. Nat Commun. 2022. PMID: 36351897 Free PMC article.

10

Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology.

Pan Z, Zhang Y, Luo J, Li D, Zhou Y, He L, Yang Q, Dong M, Tao L. Pan Z, et al. Among authors: dong m. PLoS Pathog. 2021 Jan 28;17(1):e1009197. doi: 10.1371/journal.ppat.1009197. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33507919 Free PMC article.

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