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The challenge of flavonoid/cyclodextrin complexation in a complex matrix of the quercetin, luteolin, and 3-O-methylquercetin.
Pharm Dev Technol. 2022 Jul;27(6):625-634. doi: 10.1080/10837450.2022.2098326. Epub 2022 Jul 11.
Pharm Dev Technol. 2022.
PMID: 35796030
Semi-preparative isolation and purification of phenolic compounds from Achyrocline satureioides (Lam) D.C. by high-performance counter-current chromatography.
Bianchi SE, Kaiser S, Pittol V, Doneda E, De Souza KCB, Bassani VL.
Bianchi SE, et al. Among authors: doneda e.
Phytochem Anal. 2019 Mar;30(2):182-192. doi: 10.1002/pca.2803. Epub 2018 Nov 22.
Phytochem Anal. 2019.
PMID: 30565775
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Box-Behnken Design for Extraction Optimization Followed by High Performance Countercurrent Chromatography: Production of a Flavonoid-enriched Fraction from Achyrocline Satureioides.
Pittol V, Ortega GG, Doneda E, Bianchi SE, Santos MC, Koetz M, Henriques AT, Bassani VL.
Pittol V, et al. Among authors: doneda e.
Planta Med. 2020 Jan;86(2):151-159. doi: 10.1055/a-1063-6437. Epub 2019 Nov 27.
Planta Med. 2020.
PMID: 31777054
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3-O-Methylquercetin from Achyrocline satureioides-cytotoxic activity against A375-derived human melanoma cell lines and its incorporation into cyclodextrins-hydrogels for topical administration.
Doneda E, Bianchi SE, Pittol V, Kreutz T, Scholl JN, Ibañez IL, Bracalente C, Durán H, Figueiró F, Klamt F, Bassani VL.
Doneda E, et al.
Drug Deliv Transl Res. 2021 Oct;11(5):2151-2168. doi: 10.1007/s13346-020-00882-6. Epub 2021 Jan 6.
Drug Deliv Transl Res. 2021.
PMID: 33410099
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Achyrocline satureioides compounds, achyrobichalcone and 3-O-methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines.
Bianchi SE, Pegues MA, Dias CK, Mascia F, Doneda E, Pittol V, Rao VA, Klamt F, Bassani VL.
Bianchi SE, et al. Among authors: doneda e.
IUBMB Life. 2020 Oct;72(10):2133-2145. doi: 10.1002/iub.2348. Epub 2020 Jul 25.
IUBMB Life. 2020.
PMID: 32710804
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