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Pharmacokinetics and efficacy of topical inserts containing tenofovir alafenamide fumarate and elvitegravir administered rectally in macaques.
Makarova N, Singletary T, Peet MM, Mitchell J, Holder A, Dinh C, Agrahari V, Mendoza M, Pan Y, Heneine W, Clark MR, García-Lerma JG, Smith JM, Doncel GF. Makarova N, et al. Among authors: doncel gf. EBioMedicine. 2022 Dec;86:104338. doi: 10.1016/j.ebiom.2022.104338. Epub 2022 Nov 5. EBioMedicine. 2022. PMID: 36343572 Free PMC article.
Single dose topical inserts containing tenofovir alafenamide fumarate and elvitegravir provide pre- and post-exposure protection against vaginal SHIV infection in macaques.
Dobard CW, Peet MM, Nishiura K, Holder A, Dinh C, Mitchell J, Khalil G, Pan Y, Singh ON, McCormick TJ, Agrahari V, Gupta P, Jonnalagadda S, Heneine W, Clark MR, García-Lerma JG, Doncel GF. Dobard CW, et al. Among authors: doncel gf. EBioMedicine. 2022 Dec;86:104361. doi: 10.1016/j.ebiom.2022.104361. Epub 2022 Nov 21. EBioMedicine. 2022. PMID: 36423375 Free PMC article.
Randomized controlled phase IIa clinical trial of safety, pharmacokinetics and pharmacodynamics of tenofovir and tenofovir plus levonorgestrel releasing intravaginal rings used by women in Kenya.
Mugo NR, Mudhune V, Heffron R, Thomas KK, McLellan-Lemal E, Njoroge B, Peacock S, O'Connor SM, Nyagol B, Ouma E, Ridzon R, Wiener J, Isoherranen N, Erikson DW, Ouattara LA, Yousefieh N, Jacot TA, Haaland RE, Morrison SA, Haugen HS, Thurman AR, Allen SA, Baeten JM, Samandari T, Doncel GF. Mugo NR, et al. Among authors: doncel gf. Front Reprod Health. 2023 Jun 13;5:1118030. doi: 10.3389/frph.2023.1118030. eCollection 2023. Front Reprod Health. 2023. PMID: 37383290 Free PMC article.
Extended post-exposure protection against vaginal SHIV infection with tenofovir alafenamide fumarate/elvitegravir inserts in macaques.
Makarova N, Singletary T, Peet MM, Mitchell J, Bachman S, Holder A, Dinh C, Lipscomb J, Agrahari V, Mendoza M, Pan Y, Heneine W, Clark MR, García-Lerma JG, Doncel GF, Smith JM. Makarova N, et al. Among authors: doncel gf. J Infect Dis. 2023 Dec 22:jiad599. doi: 10.1093/infdis/jiad599. Online ahead of print. J Infect Dis. 2023. PMID: 38134382
A conjoint experiment of three placebo rectal products used with receptive anal sex: results from MTN-035.
Bauermeister J, Lin W, Tingler R, Liu A, Chariyalertsak S, Hoesley C, Gonzales P, Ho K, Kayange N, Phillips TP, Johnson S, Brown E, Zemanek J, Jacobson CE, Doncel GF, Piper J; MTN-035 Protocol Team for the Microbicide Trials Network. Bauermeister J, et al. Among authors: doncel gf. J Int AIDS Soc. 2024 Mar;27(3):e26219. doi: 10.1002/jia2.26219. J Int AIDS Soc. 2024. PMID: 38494656 Free PMC article. Clinical Trial.
175 results