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Distinctive in vivo kinetics of the new σ1 receptor ligands (R)-(+)- and (S)-(-)-18F-fluspidine in porcine brain.
Brust P, Deuther-Conrad W, Becker G, Patt M, Donat CK, Stittsworth S, Fischer S, Hiller A, Wenzel B, Dukic-Stefanovic S, Hesse S, Steinbach J, Wünsch B, Lever SZ, Sabri O. Brust P, et al. Among authors: donat ck. J Nucl Med. 2014 Oct;55(10):1730-6. doi: 10.2967/jnumed.114.137562. Epub 2014 Jul 28. J Nucl Med. 2014. PMID: 25071097 Free article.
A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand.
Teodoro R, Scheunemann M, Deuther-Conrad W, Wenzel B, Fasoli FM, Gotti C, Kranz M, Donat CK, Patt M, Hillmer A, Zheng MQ, Peters D, Steinbach J, Sabri O, Huang Y, Brust P. Teodoro R, et al. Among authors: donat ck. Molecules. 2015 Oct 9;20(10):18387-421. doi: 10.3390/molecules201018387. Molecules. 2015. PMID: 26473809 Free PMC article.
Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.
Wenzel B, Mollitor J, Deuther-Conrad W, Dukic-Stefanovic S, Kranz M, Vraka C, Teodoro R, Günther R, Donat CK, Ludwig FA, Fischer S, Smits R, Wadsak W, Mitterhauser M, Steinbach J, Hoepping A, Brust P. Wenzel B, et al. Among authors: donat ck. J Med Chem. 2016 Mar 10;59(5):1800-17. doi: 10.1021/acs.jmedchem.5b01080. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26796795
LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.
Ludwig FA, Smits R, Fischer S, Donat CK, Hoepping A, Brust P, Steinbach J. Ludwig FA, et al. Among authors: donat ck. Molecules. 2016 Sep 8;21(9):1200. doi: 10.3390/molecules21091200. Molecules. 2016. PMID: 27617996 Free PMC article.
Internal dose assessment of (-)-18F-flubatine, comparing animal model datasets of mice and piglets with first-in-human results.
Sattler B, Kranz M, Starke A, Wilke S, Donat CK, Deuther-Conrad W, Patt M, Schildan A, Patt J, Smits R, Hoepping A, Schoenknecht P, Steinbach J, Brust P, Sabri O. Sattler B, et al. Among authors: donat ck. J Nucl Med. 2014 Nov;55(11):1885-92. doi: 10.2967/jnumed.114.137059. Epub 2014 Oct 6. J Nucl Med. 2014. PMID: 25286922 Free article.
Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results.
Kranz M, Sattler B, Tiepolt S, Wilke S, Deuther-Conrad W, Donat CK, Fischer S, Patt M, Schildan A, Patt J, Smits R, Hoepping A, Steinbach J, Sabri O, Brust P. Kranz M, et al. Among authors: donat ck. EJNMMI Phys. 2016 Dec;3(1):25. doi: 10.1186/s40658-016-0160-5. Epub 2016 Oct 21. EJNMMI Phys. 2016. PMID: 27770429 Free PMC article.
38 results