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Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis.
Badenes M, Amin A, González-García I, Félix I, Burbridge E, Cavadas M, Ortega FJ, de Carvalho É, Faísca P, Carobbio S, Seixas E, Pedroso D, Neves-Costa A, Moita LF, Fernández-Real JM, Vidal-Puig A, Domingos A, López M, Adrain C. Badenes M, et al. Among authors: domingos a. Mol Metab. 2020 Jan;31:67-84. doi: 10.1016/j.molmet.2019.10.006. Epub 2019 Oct 31. Mol Metab. 2020. PMID: 31918923 Free PMC article.
Sympathetic neuro-adipose connections mediate leptin-driven lipolysis.
Zeng W, Pirzgalska RM, Pereira MM, Kubasova N, Barateiro A, Seixas E, Lu YH, Kozlova A, Voss H, Martins GG, Friedman JM, Domingos AI. Zeng W, et al. Among authors: domingos ai. Cell. 2015 Sep 24;163(1):84-94. doi: 10.1016/j.cell.2015.08.055. Cell. 2015. PMID: 26406372 Free article.
Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine.
Pirzgalska RM, Seixas E, Seidman JS, Link VM, Sánchez NM, Mahú I, Mendes R, Gres V, Kubasova N, Morris I, Arús BA, Larabee CM, Vasques M, Tortosa F, Sousa AL, Anandan S, Tranfield E, Hahn MK, Iannacone M, Spann NJ, Glass CK, Domingos AI. Pirzgalska RM, et al. Among authors: domingos ai. Nat Med. 2017 Nov;23(11):1309-1318. doi: 10.1038/nm.4422. Epub 2017 Oct 9. Nat Med. 2017. PMID: 29035364 Free PMC article.
Ferritin regulates organismal energy balance and thermogenesis.
Blankenhaus B, Braza F, Martins R, Bastos-Amador P, González-García I, Carlos AR, Mahu I, Faisca P, Nunes JM, Ventura P, Hoerr V, Weis S, Guerra J, Cardoso S, Domingos A, López M, Soares MP. Blankenhaus B, et al. Among authors: domingos a. Mol Metab. 2019 Jun;24:64-79. doi: 10.1016/j.molmet.2019.03.008. Epub 2019 Mar 21. Mol Metab. 2019. PMID: 30954544 Free PMC article.
Central nicotine induces browning through hypothalamic κ opioid receptor.
Seoane-Collazo P, Liñares-Pose L, Rial-Pensado E, Romero-Picó A, Moreno-Navarrete JM, Martínez-Sánchez N, Garrido-Gil P, Iglesias-Rey R, Morgan DA, Tomasini N, Malone SA, Senra A, Folgueira C, Medina-Gomez G, Sobrino T, Labandeira-García JL, Nogueiras R, Domingos AI, Fernández-Real JM, Rahmouni K, Diéguez C, López M. Seoane-Collazo P, et al. Among authors: domingos ai. Nat Commun. 2019 Sep 6;10(1):4037. doi: 10.1038/s41467-019-12004-z. Nat Commun. 2019. PMID: 31492869 Free PMC article.
Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects.
Mahú I, Barateiro A, Rial-Pensado E, Martinéz-Sánchez N, Vaz SH, Cal PMSD, Jenkins B, Rodrigues T, Cordeiro C, Costa MF, Mendes R, Seixas E, Pereira MMA, Kubasova N, Gres V, Morris I, Temporão C, Olivares M, Sanz Y, Koulman A, Corzana F, Sebastião AM, López M, Bernardes GJL, Domingos AI. Mahú I, et al. Among authors: domingos ai. Cell Metab. 2020 Jun 2;31(6):1120-1135.e7. doi: 10.1016/j.cmet.2020.04.013. Epub 2020 May 12. Cell Metab. 2020. PMID: 32402266 Free PMC article.
Macrophages in obesity.
Pirzgalska RM, Domingos AI. Pirzgalska RM, et al. Cell Immunol. 2018 Aug;330:183-187. doi: 10.1016/j.cellimm.2018.04.014. Epub 2018 May 3. Cell Immunol. 2018. PMID: 29807623 Review.
209 results